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Preliminary evaluation of a culturally adapted CBT-based online programme for depression and anxiety from a lower middle-income country

Published online by Cambridge University Press:  26 November 2021

Madeeha Latif
Affiliation:
Sindh Institute of Physical Medicine and Rehabilitation, Dow University of Health Sciences, Karachi, Pakistan
Falahat Awan
Affiliation:
Sindh Institute of Physical Medicine and Rehabilitation, Dow University of Health Sciences, Karachi, Pakistan
Mirrat Gul
Affiliation:
Department of Preventive Cardiology, Punjab Institute of Cardiology, Lahore, Pakistan
M. Omair Husain*
Affiliation:
Department of Psychiatry, University of Toronto, Ontario, Canada Centre for Addiction and Mental Health, Toronto, Ontario, Canada
M. Ishrat Husain
Affiliation:
Department of Psychiatry, University of Toronto, Ontario, Canada Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Kumail Sayyed
Affiliation:
Pakistan Association of Cognitive Therapists, Karachi, Pakistan
Taj Magsi
Affiliation:
Pakistan Association of Cognitive Therapists, Karachi, Pakistan
Saiqa Naz
Affiliation:
Sheffield Specialist Psychotherapy Service, Sheffield, UK
Ozlem Aylem
Affiliation:
Department of Clinical, Neuro and Developmental Psychology, Van der Boechorststraat 7, Amsterdam, The Netherlands
Peter Phiri
Affiliation:
Research & Development, Southern Health NHS Foundation Trust, Southampton, UK
Muhammad Irfan
Affiliation:
Department of Psychiatry, Lady Reading Hospital, Peshawar, Pakistan
Muhammad Ayub
Affiliation:
Department of Psychiatry, Queens University, Kingston, Canada
Farooq Naeem
Affiliation:
Department of Psychiatry, University of Toronto, Ontario, Canada Centre for Addiction and Mental Health, Toronto, Ontario, Canada
*
*Corresponding author. E-mail: omair.husain@camh.ca

Abstract

Online cognitive behaviour therapy (CBT), self-help and guided self-help (GSH) interventions have been found to be efficacious and cost-effective for treatment of anxiety and depression, but there are limited data from low- and middle-income countries on culturally adapted digital interventions for these common mental disorders. The aim of this study was to investigate the feasibility and acceptability of an online culturally adapted CBT-based guided self-help (CaCBT-GSH) for patients with anxiety and depression in Pakistan. This randomized controlled trial recruited 39 participants from primary care in Karachi, Pakistan and randomized them to two groups. The intervention group received seven modules of CaCBT-GSH plus treatment as usual (TAU) over 12 weeks. The control group was a waitlist control plus TAU. The primary outcomes were feasibility and acceptability. Clinical outcomes included results from the Hospital Anxiety and Depression Scale (HADS) and the WHO Disability Assessment Schedule 2 (WHODAS 2). Assessments were carried out at baseline and at 12 weeks. All 39 individuals who met eligibility criteria for the study agreed to participate. Adherence to the intervention was excellent, with 85% (17/20) completing more than five modules. Statistically significant improvements were found in all clinical outcomes in the intervention group. This was the first trial of an online CaCBT-GSH intervention, which was found to be feasible and acceptable to Pakistani patients with anxiety and depression. CaCBT-GSH may help improve symptoms, depression, anxiety and overall functioning in this population. The results provide rationale for a larger, confirmatory randomized controlled trial of digital CaCBT-GSH.

Key learning aims

  1. (1) Leveraging digital and virtual platforms to deliver psychosocial interventions may contribute to addressing the significant treatment gap in low-resource settings.

  2. (2) CBT-informed guided self-help is feasible and acceptable in the treatment of common mental disorders in Pakistan.

  3. (3) The results of this study merit a larger, appropriately powered confirmatory randomized controlled trial to determine clinical and cost effectiveness.

Type
Original Research
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the British Association for Behavioural and Cognitive Psychotherapies

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References

Further reading

Fu, Z., Burger, H., Arjadi, R., & Bockting, C. L. H. (2020). Effectiveness of digital psychological interventions for mental health problems in low-income and middle-income countries: a systematic review and meta-analysis. The Lancet Psychiatry, 7, 851864. https://doi.org/10.1016/S2215-0366(20)30256-X CrossRefGoogle ScholarPubMed

References

Amin, R., Iqbal, A., Naeem, F., & Irfan, M. (2020). Effectiveness of a culturally adapted cognitive behavioural therapy-based guided self-help (CACBT-GSH) intervention to reduce social anxiety and enhance self-esteem in adolescents: a randomized controlled trial from Pakistan. Behavioural and Cognitive Psychotherapy, 48, 503514. https://doi.org/10.1017/s1352465820000284 CrossRefGoogle ScholarPubMed
Andrews, G., Basu, A., Cuijpers, P., Craske, M. G., McEvoy, P., English, C. L., & Newby, J. M. (2018). Computer therapy for the anxiety and depression disorders is effective, acceptable and practical health care: an updated meta-analysis. Journal of Anxiety Disorders, 55, 7078. https://doi.org/10.1016/j.janxdis.2018.01.001 CrossRefGoogle ScholarPubMed
Arjadi, R., Nauta, M. H., Scholte, W. F., Hollon, S. D., Chowdhary, N., Suryani, A. O., & Bockting, C. L. H. (2016). Guided Act and Feel Indonesia (GAF-ID) – internet-based behavioral activation intervention for depression in Indonesia: study protocol for a randomized controlled trial. Trials, 17, 455. https://doi.org/10.1186/s13063-016-1577-9 CrossRefGoogle ScholarPubMed
Arjadi, R., Nauta, M. H., Scholte, W. F., Hollon, S. D., Chowdhary, N., Suryani, A. O., Uiterwaal, C. S. P. M., & Bockting, C. L. H. (2018). Internet-based behavioural activation with lay counsellor support versus online minimal psychoeducation without support for treatment of depression: a randomised controlled trial in Indonesia. The Lancet. Psychiatry, 5, 707716. https://doi.org/10.1016/S2215-0366(18)30223-2 CrossRefGoogle ScholarPubMed
Chowdhary, N., Anand, A., Dimidjian, S., Shinde, S., Weobong, B., Balaji, M., Hollon, S. D., Rahman, A., Wilson, G. T., Verdeli, H., Araya, R., King, M., Jordans, M. J. D., Fairburn, C., Kirkwood, B., & Patel, V. (2015). The Healthy Activity Program lay counsellor delivered treatment for severe depression in India: systematic development and randomised evaluation. British Journal of Psychiatry, bjp.bp.114.161075. https://doi.org/10.1192/bjp.bp.114.161075 CrossRefGoogle Scholar
Cuijpers, P., Donker, T., van Straten, A., Li, J., & Andersson, G. (2010). Is guided self-help as effective as face-to-face psychotherapy for depression and anxiety disorders? A systematic review and meta-analysis of comparative outcome studies. Psychological Medicine, 40, 19431957. https://doi.org/10.1017/S0033291710000772 CrossRefGoogle ScholarPubMed
Cuijpers, P., Karyotaki, E., Reijnders, M., Purgato, M., & Barbui, C. (2018). Psychotherapies for depression in low- and middle-income countries: a meta-analysis. World Psychiatry, 17, 90101. https://doi.org/10.1002/wps.20493 CrossRefGoogle ScholarPubMed
Cuijpers, P., & Schuurmans, J. (2007). Self-help interventions for anxiety disorders: an overview. Current Psychiatry Reports, 9, 284290.CrossRefGoogle ScholarPubMed
Dagher, R. (2020). 2020 Digital Readiness Index: the path toward building a more inclusive, digital economy in Canada. https://gblogs.cisco.com/ca/2020/01/29/2020-digital-readiness-index-the-path-toward-building-a-more-inclusive-digital-economy-in-canada/ Google Scholar
Eaton, J., McCay, L., Semrau, M., Chatterjee, S., Baingana, F., Araya, R., Ntulo, C., Thornicroft, G., & Saxena, S. (2011). Scale up of services for mental health in low-income and middle-income countries. The Lancet, 378, 15921603. https://doi.org/10.1016/S0140-6736(11)60891-X CrossRefGoogle ScholarPubMed
Falbe-Hansen, L., Le Huray, C., Phull, B., Shakespeare, C., & Wheatley, J. (2009). Using guided self-help to treat common mental health problems: the Westminster Primary Care Psychology Service. London Journal of Primary Care, 2, 6164.CrossRefGoogle ScholarPubMed
Fu, Z., Burger, H., Arjadi, R., & Bockting, C. L. H. (2020). Effectiveness of digital psychological interventions for mental health problems in low-income and middle-income countries: a systematic review and meta-analysis. The Lancet Psychiatry, 7, 851864. https://doi.org/10.1016/S2215-0366(20)30256-X CrossRefGoogle ScholarPubMed
Gratzer, D., & Khalid-Khan, F. (2016). Internet-delivered cognitive behavioural therapy in the treatment of psychiatric illness. CMAJ: Canadian Medical Association Journal = Journal de l’Association Medicale Canadienne, 188, 263272. https://doi.org/10.1503/cmaj.150007 CrossRefGoogle ScholarPubMed
Hoeft, T. J., Fortney, J. C., Patel, V., & Unützer, J. (2018). Task-sharing approaches to improve mental health care in rural and other low-resource settings: a systematic review. Journal of Rural Health: Official Journal of the American Rural Health Association and the National Rural Health Care Association, 34, 4862. https://doi.org/10.1111/jrh.12229 CrossRefGoogle ScholarPubMed
Julious, S. A. (2005). Sample size of 12 per group rule of thumb for a pilot study. Pharmaceutical Statistics, 4, 287291. https://doi.org/10.1002/pst.185 CrossRefGoogle Scholar
Kohn, R., Ali, A. A., Puac-Polanco, V., Figueroa, C., López-Soto, V., Morgan, K., Saldivia, S., & Vicente, B. (2018). Mental health in the Americas: an overview of the treatment gap. Revista Panamericana de Salud Pública, 42. https://doi.org/10.26633/RPSP.2018.165 CrossRefGoogle Scholar
Lambert, O., & Littlefield, E. (2009). Dial growth: how handheld devices are enabling nascent economies to skip a generation of development. Finance Development, 46, 4850.Google Scholar
Lancet Global Mental Health Group, Chisholm, D., Flisher, A. J., Lund, C., Patel, V., Saxena, S., Thornicroft, G., & Tomlinson, M. (2007). Scale up services for mental disorders: a call for action. Lancet (London, England), 370, 12411252. https://doi.org/10.1016/S0140-6736(07)61242-2 Google ScholarPubMed
Lewis, T., Synowiec, C., Lagomarsino, G., & Schweitzer, J. (2012). E-health in low- and middle-income countries: findings from the Center for Health Market Innovations. Bulletin of the World Health Organization, 90, 332340. https://doi.org/10.2471/BLT.11.099820 CrossRefGoogle Scholar
Myhr, G., & Payne, K. (2006). Cost-effectiveness of cognitive-behavioural therapy for mental disorders: implications for public health care funding policy in Canada. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie, 51, 662670. https://doi.org/10.1177/070674370605101006 CrossRefGoogle ScholarPubMed
Naeem, F., Sarhandi, I., Gul, M., Khalid, M., Aslam, M., Anbrin, A., Saeed, S., Noor, M., Fatima, G., Minhas, F., Husain, N., & Ayub, M. (2014). A multicentre randomised controlled trial of a carer supervised culturally adapted CBT (CaCBT) based self-help for depression in Pakistan. Journal of Affective Disorders, 156, 224227. https://doi.org/10.1016/j.jad.2013.10.051 CrossRefGoogle ScholarPubMed
Naeem, F., Gire, N., Xiang, S., Yang, M., Syed, Y., Shokraneh, F., Adams, C., & Farooq, S. (2016). Reporting and understanding the safety and adverse effect profile of mobile apps for psychosocial interventions: an update. World Journal of Psychiatry, 6, 187191. https://doi.org/10.5498/wjp.v6.i2.187 CrossRefGoogle ScholarPubMed
Naslund, J. A., Aschbrenner, K. A., Araya, R., Marsch, L. A., Unützer, J., Patel, V., & Bartels, S. J. (2017). Digital technology for treating and preventing mental disorders in low-income and middle-income countries: a narrative review of the literature. The Lancet Psychiatry, 4, 486500. https://doi.org/10.1016/S2215-0366(17)30096-2 CrossRefGoogle ScholarPubMed
Paris, M., Silva, M., Añez-Nava, L., Jaramillo, Y., Kiluk, B. D., Gordon, M. A., Nich, C., Frankforter, T., Devore, K., Ball, S. A., & Carroll, K. M. (2018). Culturally adapted, web-based cognitive behavioral therapy for Spanish-speaking individuals with substance use disorders: a randomized clinical trial. American Journal of Public Health, 108, 15351542. https://doi.org/10.2105/AJPH.2018.304571 CrossRefGoogle ScholarPubMed
Rodriguez-Villa, E., Naslund, J., Keshavan, M., Patel, V., & Torous, J. (2020). Making mental health more accessible in light of COVID-19: Scalable digital health with digital navigators in low and middle-income countries. Asian Journal of Psychiatry, 54. https://doi.org/10.1016/j.ajp.2020.102433 CrossRefGoogle Scholar
Salamanca-Sanabria, A., Richards, D., & Timulak, L. (2019). Adapting an internet-delivered intervention for depression for a Colombian college student population: an illustration of an integrative empirical approach. Internet Interventions, 15, 7686. https://doi.org/10.1016/j.invent.2018.11.005 CrossRefGoogle ScholarPubMed
Salamanca-Sanabria, A., Richards, D., Timulak, L., Connell, S., Perilla, M. M., Parra-Villa, Y., & Castro-Camacho, L. (2020). A culturally adapted cognitive behavioral internet-delivered intervention for depressive symptoms: randomized controlled trial. JMIR Mental Health, 7, e13392. https://doi.org/10.2196/13392 CrossRefGoogle ScholarPubMed
Thase, M. E., McCrone, P., Barrett, M. S., Eells, T. D., Wisniewski, S. R., Balasubramani, G. K., Brown, G. K., & Wright, J. H. (2020). Improving cost-effectiveness and access to cognitive behavior therapy for depression: providing remote-ready, computer-assisted psychotherapy in times of crisis and beyond. Psychotherapy and Psychosomatics, 89, 307313. https://doi.org/10.1159/000508143 CrossRefGoogle ScholarPubMed
UN Foundation-Vodafone Foundation Partnership (2020). mHealth for development: the opportunity of mobile technology for healthcare in the developing world. http://www.globalproblems-globalsolutions-files.org/unf_website/assets/publications/technology/mhealth/mHealth_for_Development_full.pdf Google Scholar
Üstün, T. B., Chatterji, S., Kostanjsek, N., Rehm, J., Kennedy, C., Epping-Jordan, J., Saxena, S., von Korff, M., & Pull, C. (2010). Developing the World Health Organization Disability Assessment Schedule 2.0. Bulletin of the World Health Organization, 88, 815823. https://doi.org/10.2471/BLT.09.067231 CrossRefGoogle ScholarPubMed
Vos, T., Barber, R. M., Bell, B., Bertozzi-Villa, A., Biryukov, S., Bolliger, I., Charlson, F., Davis, A., Degenhardt, L., Dicker, D., Duan, L., Erskine, H., Feigin, V. L., Ferrari, A. J., Fitzmaurice, C., Fleming, T., Graetz, N., Guinovart, C., Haagsma, J., … & Murray, C. J. (2015). Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet, 386, 743800. https://doi.org/10.1016/S0140-6736(15)60692-4 CrossRefGoogle Scholar
WHO (2011). mHealth: new horizons for health through mobile technologies: second global survey on eHealth. World Health Organization. https://apps.who.int/iris/handle/10665/44607 Google Scholar
WHO (2017). Depression and Other Common Mental Disorders: Global Health Estimates. World Health Organization. https://apps.who.int/iris/bitstream/handle/10665/254610/WHO-MSD-MER-2017.2-eng.pdf Google Scholar
Wisniewski, H., & Torous, J. (2020). Digital navigators to implement smartphone and digital tools in care. Acta Psychiatrica Scandinavica, 141, 350355. https://doi.org/10.1111/acps.13149 CrossRefGoogle ScholarPubMed
World Bank (2020). Mobile cellular subscriptions (per 100 people) | Data. https://data.worldbank.org/indicator/IT.CEL.SETS.P2 Google Scholar
Zigmond, A. S., & Snaith, R. P. (1983). The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica, 67, 361370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x CrossRefGoogle ScholarPubMed
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