SN 533 [1-(N-ethyl-N-propylcarbamoyl)-3-propylsulphonoyl-1,2,4-triazole] toxicity, uptake, translocation, and degradation were studied in soybeans [Glycine max (L.) Merr. ‘Williams’] and peanuts (Arachis hypogaea L. ‘GK 19′). Soybeans were more sensitive than peanuts to SN 533 applied in the nutrient solution. 14C-SN 533 was absorbed by the roots of both species, and the 14C was translocated into the shoot acropetally. Although differences in the uptake and translocation of 14C-SN 533 by soybeans and peanuts were observed, these were not large enough to account for its differential toxicity. Root-absorbed 14C-SN 533 was rapidly degraded in both species, with less than 2% of the radiolabel present in either species occurring as unaltered SN 533 8 days after treatment. Excised leaflets of both species also rapidly degraded 14C-SN 533. The data indicate that the herbicide is more rapidly degraded in peanuts than in soybeans, and thin-layer chromatography of leaflet extracts showed that different polar products were formed from 14C-SN 533 in soybeans and peanuts.