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The use of hexamethyl-p-rosaniline chloride as an ingredient in poultry feed

Published online by Cambridge University Press:  17 August 2009

A. KAMYAB ,
E. MCGILL  and
J.D. FIRMAN
A. KAMYAB*
Affiliation:
University of Missouri-Columbia, 116 Animal Sciences Department, Columbia, Missouri 65211, USA
E. MCGILL
Affiliation:
University of Missouri-Columbia, 116 Animal Sciences Department, Columbia, Missouri 65211, USA
J.D. FIRMAN
Affiliation:
University of Missouri-Columbia, 116 Animal Sciences Department, Columbia, Missouri 65211, USA
*
Corresponding author: kamyaba@missouri.edu
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Abstract

Hexamethyl-p-rosaniline chloride (HRC), also known as crystal violet or gentian violet, is a water soluble, triphenylmethane dye with bacteriostactic, fungistatic and antihelminthic activities. It has a wide range of uses, from a treatment in humans to an additive for poultry feeds. In the poultry industry, this compound has been proven as a fungicidal agent in feed, a selective bactericide against gram-positive bacteria, and has demonstrated inhibitory effects against the activity and infectivity of various strains of viruses including Newcastle disease and fowl-plague virus. At normal inclusion rates (0.5 to 1 kg/MT final feed), commercial products such as GV-11 (Naremco, Inc.) failed to be detected in broiler meat. High levels of consumption of gentian violet can be toxic to animals, with the single dose LD50 for GV-11 determined to be between 2.5 and 5.0 g/kg body weight.

Keywords

hexamethyl-p-rosaniline chloridegentian violetbacteriostatfungistatpoultry
Type
Review Article
Information
World's Poultry Science Journal , Volume 65 , Issue 3 , September 2009 , pp. 475 - 480
Copyright
Copyright © World's Poultry Science Association 2009

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