While the Poisson distribution is a classical statistical model for count data, the distributional model hinges on the constraining property that its mean equal its variance. This text instead introduces the Conway-Maxwell-Poisson distribution and motivates its use in developing flexible statistical methods based on its distributional form. This two-parameter model not only contains the Poisson distribution as a special case but, in its ability to account for data over- or under-dispersion, encompasses both the geometric and Bernoulli distributions. The resulting statistical methods serve in a multitude of ways, from an exploratory data analysis tool, to a flexible modeling impetus for varied statistical methods involving count data. The first comprehensive reference on the subject, this text contains numerous illustrative examples demonstrating R code and output. It is essential reading for academics in statistics and data science, as well as quantitative researchers and data analysts in economics, biostatistics and other applied disciplines.

Stable Lévy processes lie at the intersection of Lévy processes and self-similar Markov processes. Processes in the latter class enjoy a Lamperti-type representation as the space-time path transformation of so-called Markov additive processes (MAPs). This completely new mathematical treatment takes advantage of the fact that the underlying MAP for stable processes can be explicitly described in one dimension and semi-explicitly described in higher dimensions, and uses this approach to catalogue a large number of explicit results describing the path fluctuations of stable Lévy processes in one and higher dimensions. Written for graduate students and researchers in the field, this book systemically establishes many classical results as well as presenting many recent results appearing in the last decade, including previously unpublished material. Topics explored include first hitting laws for a variety of sets, path conditionings, law-preserving path transformations, the distribution of extremal points, growth envelopes and winding behaviour.

The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and influence. 'Data science' and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? How does it all fit together? Now in paperback and fortified with exercises, this book delivers a concentrated course in modern statistical thinking. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov Chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. Each chapter ends with class-tested exercises, and the book concludes with speculation on the future direction of statistics and data science.

The twenty-first century has seen a breathtaking expansion of statistical methodology, both in scope and in influence. 'Big data', 'data science', and 'machine learning' have become familiar terms in the news, as statistical methods are brought to bear upon the enormous data sets of modern science and commerce. How did we get here? And where are we going? This book takes us on an exhilarating journey through the revolution in data analysis following the introduction of electronic computation in the 1950s. Beginning with classical inferential theories - Bayesian, frequentist, Fisherian - individual chapters take up a series of influential topics: survival analysis, logistic regression, empirical Bayes, the jackknife and bootstrap, random forests, neural networks, Markov chain Monte Carlo, inference after model selection, and dozens more. The distinctly modern approach integrates methodology and algorithms with statistical inference. The book ends with speculation on the future direction of statistics and data science.

The case-control approach is a powerful method for investigating factors that may explain a particular event. It is extensively used in epidemiology to study disease incidence, one of the best-known examples being Bradford Hill and Doll's investigation of the possible connection between cigarette smoking and lung cancer. More recently, case-control studies have been increasingly used in other fields, including sociology and econometrics. With a particular focus on statistical analysis, this book is ideal for applied and theoretical statisticians wanting an up-to-date introduction to the field. It covers the fundamentals of case-control study design and analysis as well as more recent developments, including two-stage studies, case-only studies and methods for case-control sampling in time. The latter have important applications in large prospective cohorts which require case-control sampling designs to make efficient use of resources. More theoretical background is provided in an appendix for those new to the field.

Interest in the skew-normal and related families of distributions has grown enormously over recent years, as theory has advanced, challenges of data have grown, and computational tools have made substantial progress. This comprehensive treatment, blending theory and practice, will be the standard resource for statisticians and applied researchers. Assuming only basic knowledge of (non-measure-theoretic) probability and statistical inference, the book is accessible to the wide range of researchers who use statistical modelling techniques. Guiding readers through the main concepts and results, it covers both the probability and the statistics sides of the subject, in the univariate and multivariate settings. The theoretical development is complemented by numerous illustrations and applications to a range of fields including quantitative finance, medical statistics, environmental risk studies, and industrial and business efficiency. The author's freely available R package sn, available from CRAN, equips readers to put the methods into action with their own data.

This book introduces in a systematic manner a general nonparametric theory of statistics on manifolds, with emphasis on manifolds of shapes. The theory has important and varied applications in medical diagnostics, image analysis, and machine vision. An early chapter of examples establishes the effectiveness of the new methods and demonstrates how they outperform their parametric counterparts. Inference is developed for both intrinsic and extrinsic Fréchet means of probability distributions on manifolds, then applied to shape spaces defined as orbits of landmarks under a Lie group of transformations - in particular, similarity, reflection similarity, affine and projective transformations. In addition, nonparametric Bayesian theory is adapted and extended to manifolds for the purposes of density estimation, regression and classification. Ideal for statisticians who analyze manifold data and wish to develop their own methodology, this book is also of interest to probabilists, mathematicians, computer scientists, and morphometricians with mathematical training.

We live in a new age for statistical inference, where modern scientific technology such as microarrays and fMRI machines routinely produce thousands and sometimes millions of parallel data sets, each with its own estimation or testing problem. Doing thousands of problems at once is more than repeated application of classical methods. Taking an empirical Bayes approach, Bradley Efron, inventor of the bootstrap, shows how information accrues across problems in a way that combines Bayesian and frequentist ideas. Estimation, testing and prediction blend in this framework, producing opportunities for new methodologies of increased power. New difficulties also arise, easily leading to flawed inferences. This book takes a careful look at both the promise and pitfalls of large-scale statistical inference, with particular attention to false discovery rates, the most successful of the new statistical techniques. Emphasis is on the inferential ideas underlying technical developments, illustrated using a large number of real examples.