Book contents
- Frontmatter
- Contents
- CONTRIBUTORS
- PREFACE
- Chap. 1 CELL INJURY AND CELL DEATH
- Chap. 2 CLEAN AND ASEPTIC TECHNIQUE AT THE BEDSIDE
- Chap. 3 NEW ANTIMICROBIALS
- Chap. 4 IMMUNOMODULATORS AND THE “BIOLOGICS” IN CUTANEOUS EMERGENCIES
- Chap. 5 CRITICAL CARE: STUFF YOU REALLY, REALLY NEED TO KNOW
- Chap. 6 ACUTE SKIN FAILURE: CONCEPT, CAUSES, CONSEQUENCES, AND CARE
- Chap. 7 CUTANEOUS SYMPTOMS AND NEONATAL EMERGENCIES
- Chap. 8 NECROTIZING SOFT-TISSUE INFECTIONS, INCLUDING NECROTIZING FASCIITIS
- Chap. 9 LIFE-THREATENING BACTERIAL SKIN INFECTIONS
- Chap. 10 BACTEREMIA, SEPSIS, SEPTIC SHOCK, AND TOXIC SHOCK SYNDROME
- Chap. 11 STAPHYLOCOCCAL SCALDED SKIN SYNDROME
- Chap. 12 LIFE-THREATENING CUTANEOUS VIRAL DISEASES
- Chap. 13 LIFE-THREATENING CUTANEOUS FUNGAL AND PARASITIC DISEASES
- Chap. 14 LIFE-THREATENING STINGS, BITES, AND MARINE ENVENOMATIONS
- Chap. 15 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS I: STEVENS–JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS
- Chap. 16 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS II: DRESS SYNDROME AND SERUM SICKNESS-LIKE REACTION
- Chap. 17 SEVERE, ACUTE COMPLICATIONS OF DERMATOLOGIC THERAPIES
- Chap. 18 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS I: URTICARIA, ANGIOEDEMA, MASTOCYTOSIS, AND ANAPHYLAXIS
- Chap. 19 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS II: OTHER HYPERSENSITIVITIES AND IMMUNE DEFECTS, INCLUDING HIV
- Chap. 20 GRAFT VERSUS HOST DISEASE
- Chap. 21 ERYTHRODERMA/EXFOLIATIVE DERMATITIS
- Chap. 22 ACUTE, SEVERE BULLOUS DERMATOSES
- Chap. 23 EMERGENCY MANAGEMENT OF PURPURA AND VASCULITIS, INCLUDING PURPURA FULMINANS
- Chap. 24 EMERGENCY MANAGEMENT OF CONNECTIVE TISSUE DISORDERS AND THEIR COMPLICATIONS
- Chap. 25 SKIN SIGNS OF SYSTEMIC INFECTIONS
- Chap. 26 SKIN SIGNS OF SYSTEMIC NEOPLASTIC DISEASES AND PARANEOPLASTIC CUTANEOUS SYNDROMES
- Chap. 27 BURN INJURY
- Chap. 28 EMERGENCY DERMATOSES OF THE ANORECTAL REGIONS
- Chap. 29 EMERGENCY MANAGEMENT OF SEXUALLY TRANSMITTED DISEASES AND OTHER GENITOURETHRAL DISORDERS
- Chap. 30 EMERGENCY MANAGEMENT OF ENVIRONMENTAL SKIN DISORDERS: HEAT, COLD, ULTRAVIOLET LIGHT INJURIES
- Chap. 31 ENDOCRINOLOGIC EMERGENCIES IN DERMATOLOGY
- Chap. 32 EMERGENCY MANAGEMENT OF SKIN TORTURE AND SELF-INFLICTED DERMATOSES
- Chap. 33 SKIN SIGNS OF POISONING
- Chap. 34 DISASTER PLANNING: MASS CASUALTY MANAGEMENT
- Chap. 35 CATASTROPHES IN COSMETIC PROCEDURES
- Chap. 36 LIFE-THREATENING DERMATOSES IN TRAVELERS
- Index
- References
Chap. 22 - ACUTE, SEVERE BULLOUS DERMATOSES
Published online by Cambridge University Press: 07 September 2011
- Frontmatter
- Contents
- CONTRIBUTORS
- PREFACE
- Chap. 1 CELL INJURY AND CELL DEATH
- Chap. 2 CLEAN AND ASEPTIC TECHNIQUE AT THE BEDSIDE
- Chap. 3 NEW ANTIMICROBIALS
- Chap. 4 IMMUNOMODULATORS AND THE “BIOLOGICS” IN CUTANEOUS EMERGENCIES
- Chap. 5 CRITICAL CARE: STUFF YOU REALLY, REALLY NEED TO KNOW
- Chap. 6 ACUTE SKIN FAILURE: CONCEPT, CAUSES, CONSEQUENCES, AND CARE
- Chap. 7 CUTANEOUS SYMPTOMS AND NEONATAL EMERGENCIES
- Chap. 8 NECROTIZING SOFT-TISSUE INFECTIONS, INCLUDING NECROTIZING FASCIITIS
- Chap. 9 LIFE-THREATENING BACTERIAL SKIN INFECTIONS
- Chap. 10 BACTEREMIA, SEPSIS, SEPTIC SHOCK, AND TOXIC SHOCK SYNDROME
- Chap. 11 STAPHYLOCOCCAL SCALDED SKIN SYNDROME
- Chap. 12 LIFE-THREATENING CUTANEOUS VIRAL DISEASES
- Chap. 13 LIFE-THREATENING CUTANEOUS FUNGAL AND PARASITIC DISEASES
- Chap. 14 LIFE-THREATENING STINGS, BITES, AND MARINE ENVENOMATIONS
- Chap. 15 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS I: STEVENS–JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS
- Chap. 16 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS II: DRESS SYNDROME AND SERUM SICKNESS-LIKE REACTION
- Chap. 17 SEVERE, ACUTE COMPLICATIONS OF DERMATOLOGIC THERAPIES
- Chap. 18 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS I: URTICARIA, ANGIOEDEMA, MASTOCYTOSIS, AND ANAPHYLAXIS
- Chap. 19 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS II: OTHER HYPERSENSITIVITIES AND IMMUNE DEFECTS, INCLUDING HIV
- Chap. 20 GRAFT VERSUS HOST DISEASE
- Chap. 21 ERYTHRODERMA/EXFOLIATIVE DERMATITIS
- Chap. 22 ACUTE, SEVERE BULLOUS DERMATOSES
- Chap. 23 EMERGENCY MANAGEMENT OF PURPURA AND VASCULITIS, INCLUDING PURPURA FULMINANS
- Chap. 24 EMERGENCY MANAGEMENT OF CONNECTIVE TISSUE DISORDERS AND THEIR COMPLICATIONS
- Chap. 25 SKIN SIGNS OF SYSTEMIC INFECTIONS
- Chap. 26 SKIN SIGNS OF SYSTEMIC NEOPLASTIC DISEASES AND PARANEOPLASTIC CUTANEOUS SYNDROMES
- Chap. 27 BURN INJURY
- Chap. 28 EMERGENCY DERMATOSES OF THE ANORECTAL REGIONS
- Chap. 29 EMERGENCY MANAGEMENT OF SEXUALLY TRANSMITTED DISEASES AND OTHER GENITOURETHRAL DISORDERS
- Chap. 30 EMERGENCY MANAGEMENT OF ENVIRONMENTAL SKIN DISORDERS: HEAT, COLD, ULTRAVIOLET LIGHT INJURIES
- Chap. 31 ENDOCRINOLOGIC EMERGENCIES IN DERMATOLOGY
- Chap. 32 EMERGENCY MANAGEMENT OF SKIN TORTURE AND SELF-INFLICTED DERMATOSES
- Chap. 33 SKIN SIGNS OF POISONING
- Chap. 34 DISASTER PLANNING: MASS CASUALTY MANAGEMENT
- Chap. 35 CATASTROPHES IN COSMETIC PROCEDURES
- Chap. 36 LIFE-THREATENING DERMATOSES IN TRAVELERS
- Index
- References
Summary
A VARIETY OF SKIN diseases may present with the appearance of blisters (Table 22.1). The skin reacts with the formation of vesicles or larger bullae to a number of external physical, chemical, and biological insults. Adverse reactions to systemic or topically applied drugs occupy an important place in the differential diagnosis of blistering eruptions. Bullous lesions can also occur as a manifestation of systemic diseases, as is the case of the bullae seen in diabetic patients. Atypical blistering forms of several inflammatory dermatoses exist, such as bullous lichen planus, bullous morphea, or bullous mycosis fungoides. In all these cases, blistering lesions are infrequent and temporary, in contrast to a group of chronic cutaneous disorders referred to as “bullous dermatoses,” where vesiculobullous lesions are the main and characteristic clinical feature. Some bullous dermatoses are due to genetically determined loss of basic structural elements in the skin that maintain the cohesion between the keratinocytes in the epidermis, or between the epidermal layer and the dermis within the basement membrane zone (BMZ). The majority of bullous dermatoses, however, are acquired organ-specific autoimmune diseases in which the autoantibodies target structural proteins in the skin. These disorders constitute one of the major sources of morbidity and mortality in dermatology.
- Type
- Chapter
- Information
- Emergency Dermatology , pp. 215 - 232Publisher: Cambridge University PressPrint publication year: 2011