Throughout its 200 years, the Museu Nacional (National Museum) in Rio de Janeiro has been the principal museum of natural history in Brazil. It certainly has been among the most important research institutions in the Americas. Many of the greatest national and international scholars worked in or visited its collections, exhibitions, and laboratories. Botanists, zoologists, ecologists, geologists, paleontologists, anthropologists, archaeologists, and so many other scientists frequented the research facilities of the São Cristóvão Palace, its hallways, internal gardens, associated buildings, and park. They established friendships, scientific partnerships, and antagonisms, engaging in intense and productive exchanges that advanced science in each discipline yet with a multidisciplinary spirit. This thriving space, which we all always referred to as “our home,” was utterly destroyed by the tragedy of September 2018, when we watched in astonishment as the fire consumed our lives.