A single perspective cannot explain the entirety of serial murder. In psychology, we promote a biopsychosocial model of understanding any behavior or mental process. The author provides a summary of various perspectives, starting with behavioral neuroscience (i.e., biopsychology). She summarizes direct evidence from case studies showing neural issues in serial murderers, implied evidence of brain dysfunction of serial murders, and evidence of no neural issues in serial murderers. She then discusses the biological correlates of violence in general. The case of MSK Joseph DeAngelo highlights crime solved through forensic genetic genealogy.