This chapter investigates the impact of caching in the interference networks. First, we briefly review the basics of some classic interference networks and the corresponding interference management techniques. Then we review an interference network with caches equipped at all transmitters and receivers, termed as cache-aided interference network. The information-theoretic metric normalized delivery time (NDT) is introduced to characterize the system performance. The NDT in the cache-aided interference network is discussed for both single-antenna and multiple-antenna cases. It is shown that with different cache sizes, the network topology can be opportunistically changed to different classic interference networks, which leverages local caching gain, coded multicasting gain, and transmitter cooperation gain (via interference alignment and interference neutralization). Finally, the NDT results are extended to the partially connected interference network.