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44B - There Is No Place for Natural and Mild Stimulation IVF

Against

from Section VIII - Ovarian Stimulation

Published online by Cambridge University Press:  25 November 2021

Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

Optimal IVF entails establishing the balance between safety, oocyte/embryo quality, pregnancy and live birth outcomes, patient views and cost. Conventional ovarian stimulation (cOS) may well result in good outcomes for the majority of couples undergoing IVF. However, for certain cohorts of patients this method may result in suboptimal responses and therefore outcomes. The question is not if natural and mild stimulation (mOS) IVF are better than conventional, but if there is no place for these at all. We should not treat all of our patients the same and must acknowledge that dismissing these protocols from the armoury of our medical practice is a mistake. As will become clear from the debate, the statement that ‘There is no place for natural and mild stimulation IVF’ is simply wrong.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

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Practice Committee of the American Society for Reproductive Medicine. Comparison of pregnancy rates for poor responders using IVF with mild ovarian stimulation versus conventional IVF: a guideline. Fertil Steril. 2018;109(6):993–9.Google Scholar

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