The Peopling of Europe

doi:10.1017/CBO9781139167222.014

Chapter 13 - The Peopling of Europe

Published online by Cambridge University Press: 05 June 2012

Barbara Arredi ,

Estella S. Poloni and

Chris Tyler-Smith

Edited by

Michael H. Crawford

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Barbara Arredi: Affiliation:
University of Padua
Estella S. Poloni: Affiliation:
University of Geneva
Chris Tyler-Smith: Affiliation:
The Wellcome Trust Sanger Institute
Michael H. Crawford: Affiliation:
University of Kansas

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Summary

Although hominins were present in Europe as early as ~780 thousand years ago, there is broad agreement that these archaic humans, including Neanderthals, contributed little to the contemporary European gene pool. In contrast, there is vigorous debate about the relative contributions of humans who entered in the Upper Paleolithic and Neolithic. Here, we argue that the Y-chromosomal diversity pattern is likely to have a largely Neolithic or later origin. In addition to the genome-wide influences resulting from migration, admixture and drift, the effects of positive selection are detectable around some genes, such as lactase. Studies of species associated with humans, e.g. cattle, are providing additional insights.

Why study Europe?

Introductory remarks: why Europe?

The western edge of the Asian continent has a special status in studies of history, prehistory, anthropology and many other fields, more because of the origin of the people conducting these studies than the properties of the area. It is conventionally considered as a continent in its own right, Europe, although the geographical justification for this is difficult to see and a clear definition of parts of its eastern boundary, such as between the Urals and Bosphorus, is not easy to establish. Furthermore, much of the terminology we use and attempt to apply to the rest of the world, ‘Stone Age’, ‘Bronze Age’, etc. derives from studies of Europe. Now that we can take a more global view of some of these matters, does Europe still provide a legitimate unit of enquiry?

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Type: Chapter
Information: Anthropological Genetics
Theory, Methods and Applications
, pp. 380 - 408

DOI: https://doi.org/10.1017/CBO9781139167222.014 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2006

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References

Abdennaji Guenounou, B., Loueslati, B. Y., Buhler, S., Hmida, S., Ennafaa, H., Khodjet-Elkhil, H., Moojat, N., Dridi, A., Boukef, K., Ben Ammar Elgaaied, A. and Sanchez-Mazas, A. (2006). HLA class II genetic diversity in southern Tunisia and the Mediterranean area. Int J Immunogenet, 33, 93–103CrossRef Google Scholar PubMed

Ammerman, A. J. and Cavalli-Sforza, L. L. (1984). The Neolithic Transition and the Genetics of Populations in Europe. Princeton, NJ: Princeton University PressCrossRef Google Scholar

Aoki, K. (2002). Sexual selection as a cause of human skin colour variation: Darwin's hypothesis revisited. Ann Hum Biol, 29, 589–608CrossRef Google Scholar PubMed

Arredi, B., Poloni, E. S., Paracchini, S., Zerjal, T., Fathallah, D. M., Makrelouf, M., Pascali, V. L., Novelletto, A. and Tyler-Smith, C. (2004). A predominantly Neolithic origin for Y-chromosomal DNA variation in North Africa. Am J Hum Genet, 75, 338–45CrossRef Google Scholar PubMed

Barac, L., Pericic, M., Klaric, I. M., Rootsi, S., Janicijevic, B., Kivisild, T., Parik, J., Rudan, I., Villems, R. and Rudan, P. (2003). Y chromosomal heritage of Croatian population and its island isolates. Eur J Hum Genet, 11, 535–42CrossRef Google Scholar

Barbujani, G. and Bertorelle, G. (2001). Genetics and the population history of Europe. Proc Natl Acad Sci USA, 98, 22–5CrossRef Google Scholar PubMed

Barbujani, G., Bertorelle, G. and Chikhi, L. (1998). Evidence for Paleolithic and Neolithic gene flow in Europe. Am J Hum Genet, 62, 488–92CrossRef Google Scholar

Barbujani, G. and Goldstein, D. B. (2004). Africans and Asians abroad: genetic diversity in Europe. Annu Rev Genomics Hum Genet, 5, 119–50CrossRef Google Scholar

Barbujani, G., Pilastro, A., Domenico, S. and Renfrew, C. (1994). Genetic variation in North Africa and Eurasia: Neolithic demic diffusion vs. Paleolithic colonisation. Am J Phys Anthropol, 95, 137–54CrossRef Google Scholar PubMed

Barsh, G. S. (2003). What controls variation in human skin color?PLoS Biol, 1, E27CrossRef Google Scholar PubMed

Beja-Pereira, A., Luikart, G., England, P. R., Bradley, D. G., Jann, O. C., Bertorelle, G., Chamberlain, A. T., Nunes, T. P., Metodiev, S., Ferrand, N. and Erhardt, G. (2003). Gene-culture coevolution between cattle milk protein genes and human lactase genes. Nat Genet, 35, 311–13CrossRef Google Scholar PubMed

Bermudez de Castro, J. M., Arsuaga, J. L., Carbonell, E., Rosas, A., Martinez, I. and Mosquera, M. (1997). A hominid from the lower Pleistocene of Atapuerca, Spain: possible ancestor to Neandertals and modern humans. Science, 276, 1392–5CrossRef Google Scholar PubMed

Bersaglieri, T., Sabeti, P. C., Patterson, N., Vanderploeg, T., Schaffner, S. F., Drake, J. A., Rhodes, M., Reich, D. E. and Hirschhorn, J. N. (2004). Genetic signatures of strong recent positive selection at the lactase gene. Am J Hum Genet, 74, 1111–20CrossRef Google Scholar PubMed

Bosch, E., Calafell, F., Comas, D., Oefner, P. J., Underhill, P. A. and Bertranpetit, J. (2001). High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula. Am J Hum Genet, 68, 1019–29CrossRef Google Scholar

Bradford, L. D. (2002). CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics, 3, 229–43CrossRef Google Scholar PubMed

Brion, M., Quintans, B., Zarrabeitia, M., Gonzalez-Neira, A., Salas, A., Lareu, V., Tyler-Smith, C. and Carracedo, A. (2004). Micro-geographical differentiation in Northern Iberia revealed by Y-chromosomal DNA analysis. Gene, 329, 17–25CrossRef Google Scholar PubMed

Bruford, M. W., Bradley, D. G. and Luikart, G. (2003). DNA markers reveal the complexity of livestock domestication. Nat Rev Genet, 4, 900–10CrossRef Google Scholar PubMed

Capelli, C., Redhead, N., Romano, V., Cali, F., Lefranc, G., Delague, V., Megarbane, A., Felice, A. E., Pascali, V. L., Neophytou, P. I., Poulli, Z., Novelletto, A., Malaspina, P., Terrenato, L., Berebbi, A., Fellous, M., Thomas, M. G. and Goldstein, D. B. (2006). Population structure in the Mediterranean basin: a Y chromosome perspective. Ann Hum Genet, 70, 207–25CrossRef Google Scholar PubMed

Cavalli-Sforza, L. L., Menozzi, P. and Piazza, A. (1994). The History and Geography of Human Genes. Princeton, NJ: Princeton University Press.Google Scholar

Chikhi, L., Nichols, R. A., Barbujani, G. and Beaumont, M. A. (2002). Y genetic data support the Neolithic demic diffusion model. Proc Natl Acad Sci USA, 99, 11008–13CrossRef Google Scholar

Cinnioglu, C., King, R., Kivisild, T., Kalfoglu, E., Atasoy, S., Cavalleri, G. L., Lillie, A. S., Roseman, C. C., Lin, A. A., Prince, K., Oefner, P. J., Shen, P., Semino, O., Cavalli-Sforza, L. L. and Underhill, P. A. (2004). Excavating Y-chromosome haplotype strata in Anatolia. Hum Genet, 114, 127–48CrossRef Google Scholar PubMed

Cordaux, R., Deepa, E., Vishwanathan, H. and Stoneking, M. (2004). Genetic evidence for the demic diffusion of agriculture to India. Science, 304, 1125CrossRef Google Scholar PubMed

Currat, M. and Excoffier, L. (2004). Modern humans did not admix with Neanderthals during their range expansion into Europe. PLoS Biol, 2, e421CrossRef Google Scholar

Currat, M. and Excoffier, L. (2005). The effect of the Neolithic expansion on European molecular diversity. Proc R Soc B, 272, 679–88CrossRef Google Scholar PubMed

Diamond, J. and Bellwood, P. (2003). Farmers and their languages: the first expansions. Science, 300, 597–603CrossRef Google Scholar PubMed

Duarte, C., Maurício, J., Pettitt, P. B., Souto, P., Trinkaus, E., Plicht, H. and Zilhão, J. (1999). The early Upper Paleolithic human skeleton from the Abrigo do Lagar Velho (Portugal) and modern human emergence in Iberia. Proc Natl Acad Sci USA, 96, 7604–9CrossRef Google Scholar PubMed

Dupanloup, I., Bertorelle, G., Chikhi, L. and Barbujani, G. (2004). Estimating the impact of prehistoric admixture on the genome of Europeans. Mol Biol Evol, 21, 1361–72CrossRef Google Scholar PubMed

Dupuy, B. M., Stenersen, M., Egeland, T. and Olaisen, B. (2004). Y-chromosomal microsatellite mutation rates: differences in mutation rate between and within loci. Hum Mutat, 23, 117–24CrossRef Google Scholar PubMed

Enattah, N. S., Sahi, T., Savilahti, E., Terwilliger, J. D., Peltonen, L. and Jarvela, I. (2002). Identification of a variant associated with adult-type hypolactasia. Nat Genet, 30, 233–7CrossRef Google Scholar PubMed

Falush, D., Wirth, T., Linz, B., Pritchard, J. K., Stephens, M., Kidd, M., Blaser, M. J., Graham, D. Y., Vacher, S., Perez-Perez, G. I., Yamaoka, Y., Megraud, F., Otto, K., Reichard, U., Katzowitsch, E., Wang, X., Achtman, M. and Suerbaum, S. (2003). Traces of human migrations in Helicobacter pylori populations. Science, 299, 1582–5CrossRef Google Scholar PubMed

Forster, P. (2004). Ice Ages and the mitochondrial DNA chronology of human dispersals: a review. Philos Trans R Soc Lond B Biol Sci, 359, 255–64CrossRef Google Scholar PubMed

Gray, R. D. and Atkinson, Q. D. (2003). Language-tree divergence times support the Anatolian theory of Indo-European origin. Nature, 426, 435–9CrossRef Google Scholar PubMed

Harding, R. M., Healy, E., Ray, A. J., Ellis, N. S., Flanagan, N., Todd, C., Dixon, C., Sajantila, A., Jackson, I. J., Birch-Machin, M. A. and Rees, J. L. (2000). Evidence for variable selective pressures at MC1R. Am J Hum Genet, 66, 1351–61CrossRef Google Scholar PubMed

Hardy, J., Pittman, A., Myers, A., Gwinn-Hardy, K., Fung, H. C., Silva, R., Hutton, M. and Duckworth, J. (2005). Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens. Biochem Soc Trans, 33, 582–5CrossRef Google Scholar PubMed

Ho, S. Y. and Larson, G. (2006). Molecular clocks: when times are a-changin'. Trends Genet, 22, 79–83CrossRef Google Scholar

Jobling, M. A., Hurles, M. E. and Tyler-Smith, C. (2004). Human Evolutionary Genetics. New York and Abingdon: Garland Science.Google Scholar

Jobling, M. A. and Tyler-Smith, C. (2003). The human Y chromosome: an evolutionary marker comes of age. Nat Rev Genet, 4, 598–612CrossRef Google Scholar PubMed

Kayser, M., Roewer, L., Hedman, M., Henke, L., Henke, J., Brauer, S., Kruger, C., Krawczak, M., Nagy, M., Dobosz, T., Szibor, R., Knijff, P., Stoneking, M. and Sajantila, A. (2000). Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs. Am J Hum Genet, 66, 1580–8CrossRef Google Scholar PubMed

Klopfstein, S., Currat, M. and Excoffier, L. (2006). The fate of mutations surfing on the wave of a range expansion. Mol Biol Evol, 23, 482–90CrossRef Google Scholar PubMed

Krings, M., Capelli, C., Tschentscher, F., Geisert, H., Meyer, S., Haeseler, A., Grossschmidt, K., Possnert, G., Paunovic, M. and Pääbo, S. (2000). A view of Neandertal genetic diversity. Nat Genet, 26, 144–6CrossRef Google Scholar PubMed

Krings, M., Stone, A., Schmitz, R. W., Krainitzki, H., Stoneking, M. and Pääbo, S. (1997). Neandertal DNA sequences and the origin of modern humans. Cell, 90, 19–30CrossRef Google Scholar PubMed

Lamason, R. L., Mohideen, M. A., Mest, J. R., Wong, A. C., Norton, H. L., Aros, M. C., Jurynec, M. J., Mao, X., Humphreville, V. R., Humbert, J. E., Sinha, S., Moore, J. L., Jagadeeswaran, P., Zhao, W., Ning, G., Makalowska, I., McKeigue, P. M., O'Donnell, D., Kittles, R., Parra, E. J., Mangini, N. J., Grunwald, D. J., Shriver, M. D., Canfield, V. A. and Cheng, K. C. (2005). SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science, 310, 1782–6CrossRef Google Scholar PubMed

Macpherson, J. M., Ramachandran, S., Diamond, L. and Feldman, M. W. (2004). Demographic estimates from Y chromosome microsatellite polymorphisms: analysis of a worldwide sample. Hum Genomics, 1, 345–54CrossRef Google Scholar PubMed

McVean, G. A., Myers, S. R., Hunt, S., Deloukas, P., Bentley, D. R. and Donnelly, P. (2004). The fine-scale structure of recombination rate variation in the human genome. Science, 304, 581–4CrossRef Google Scholar PubMed

Mellars, P. (2006). A new radiocarbon revolution and the dispersal of modern humans in Eurasia. Nature, 439, 931–5CrossRef Google Scholar PubMed

Mulcare, C. A., Weale, M. E., Jones, A. L., Connell, B., Zeitlyn, D., Tarekegn, A., Swallow, D. M., Bradman, N. and Thomas, M. G. (2004). The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans. Am J Hum Genet, 74, 1102–10CrossRef Google Scholar PubMed

Myles, S., Bouzekri, N., Haverfield, E., Cherkaoui, M., Dugoujon, J. M. and Ward, R. (2005). Genetic evidence in support of a shared Eurasian-North African dairying origin. Hum Genet, 117, 34–42CrossRef Google Scholar PubMed

Nordborg, M. (1998). On the probability of Neanderthal ancestry. Am J Hum Genet, 63, 1237–40CrossRef Google Scholar PubMed

Ovchinnikov, I. V., Götherström, A., Romanova, G. P., Kharitonov, V. M., Liden, K. and Goodwin, W. (2000). Molecular analysis of Neanderthal DNA from the northern Caucasus. Nature, 404, 490–3CrossRef Google Scholar PubMed

Petit, J. R., Jouzel, J., Raynaud, D., Barkov, N. I., Barnola, J.-M., Basile, I., Bender, M., Chappellaz, J., Davis, M., Delayque, G., M. Delmotte, M., Kotlyakov, V. M., Legrand, M., Lipenkov, V. Y., Lorius, C., Pepin, L., Ritz, C., Saltzman, E. and Stievenard, M. (1999). Climate and atmospheric history of the past 420,000 years from the Vostok ice core, Antarctica. Nature, 399, 429–36CrossRef Google Scholar

Pinhasi, R., Fort, J. and Ammerman, A. J. (2005). Tracing the origin and spread of agriculture in Europe. PLoS Biol, 3, e410CrossRef Google Scholar

Pritchard, J. K., Stephens, M. and Donnelly, P. (2000). Inference of population structure using multilocus genotype data. Genetics, 155, 945–59Google Scholar PubMed

Rees, J. L. (2003). Genetics of hair and skin color. Annu Rev Genet, 37, 67–90CrossRef Google Scholar PubMed

Reich, D. E., Cargill, M., Bolk, S., Ireland, J., Sabeti, P. C., Richter, D. J., Lavery, T., Kouyoumjian, R., Farhadian, S. F., Ward, R. and Lander, E. S. (2001). Linkage disequilibrium in the human genome. Nature, 411, 199–204CrossRef Google Scholar PubMed

Renfrew, C. (2003). ‘The emerging synthesis’: the archaeogenetics of farming/language dispersals and other spread zones. In Examining the Farming/Language Dispersal Hypothesis, eds. Bellwood, P. and Renfrew, C.. McDonald Institute for Archaeological Research, Cambridge, UK, pp. 3–16.Google Scholar

Richards, M., Corte-Real, H., Forster, P., Macaulay, V., Wilkinson-Herbots, H., Demaine, A., Papiha, S., Hedges, R., Bandelt, H. J. and Sykes, B. (1996). Paleolithic and Neolithic lineages in the European mitochondrial gene pool. Am J Hum Genet, 59, 185–203Google Scholar PubMed

Richards, M., Macaulay, V., Hickey, E., Vega, E., Sykes, B., Guida, V., Rengo, C., Sellitto, D., Cruciani, F., Kivisild, T., Villems, R., Thomas, M., Rychkov, S., Rychkov, O., Rychkov, Y., Golge, M., Dimitrov, D., Hill, E., Bradley, D., Romano, V., Cali, F., Vona, G., Demaine, A., Papiha, S., Triantaphyllidis, C., Stefanescu, G., Hatina, J., Belledi, M., Di Rienzo, A., Novelletto, A., Oppenheim, A., Norby, S., Al-Zaheri, N., Santachiara-Benerecetti, S., Scozari, R., Torroni, A. and Bandelt, H. J. (2000). Tracing European founder lineages in the Near Eastern mtDNA pool. Am J Hum Genet, 67, 1251–76CrossRef Google Scholar PubMed

Roewer, L., Croucher, P. J., Willuweit, S., Lu, T. T., Kayser, M., Lessig, R., Knijff, P., Jobling, M. A., Tyler-Smith, C. and Krawczak, M. (2005). Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Hum Genet, 116, 279–91CrossRef Google Scholar PubMed

Rosenberg, N. A., Pritchard, J. K., Weber, J. L., Cann, H. M., Kidd, K. K., Zhivotovsky, L. A. and Feldman, M. W. (2002). Genetic structure of human populations. Science, 298, 2381–5CrossRef Google Scholar PubMed

Rosser, Z. H., Zerjal, T., Hurles, M. E., Adojaan, M., Alavantic, D., Amorim, A., Amos, W., Armenteros, M., Arroyo, E., Barbujani, G., Beckman, G., Beckman, L., Bertranpetit, J., Bosch, E., Bradley, D. G., Brede, G., Cooper, G., Corte-Real, H. B., Knijff, P., Decorte, R., Dubrova, Y. E., Evgrafov, O., Gilissen, A., Glisic, S., Golge, M., Hill, E. W., Jeziorowska, A., Kalaydjieva, L., Kayser, M., Kivisild, T., Kravchenko, S. A., Krumina, A., Kucinskas, V., Lavinha, J., Livshits, L. A., Malaspina, P., Maria, S., McElreavey, K., Meitinger, T. A., Mikelsaar, A. V., Mitchell, R. J., Nafa, K., Nicholson, J., Norby, S., Pandya, A., Parik, J., Patsalis, P. C., Pereira, L., Peterlin, B., Pielberg, G., Prata, M. J., Previdere, C., Roewer, L., Rootsi, S., Rubinsztein, D. C., Saillard, J., Santos, F. R., Stefanescu, G., Sykes, B. C., Tolun, A., Villems, R., Tyler-Smith, C. and Jobling, M. A. (2000). Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language. Am J Hum Genet, 67, 1526–43CrossRef Google Scholar PubMed

Schmitz, R. W., Serre, D., Bonani, G., Feine, S., Hillgruber, F., Krainitzki, H., Paabo, S. and Smith, F. H. (2002). The Neandertal type site revisited: interdisciplinary investigations of skeletal remains from the Neander Valley, Germany. Proc Natl Acad Sci USA, 99, 13342–7CrossRef Google Scholar PubMed

Semino, O., Passarino, G., Oefner, P. J., Lin, A. A., Arbuzova, S., Beckman, L. E., Benedictis, G., Francalacci, P., Kouvatsi, A., Limborska, S., Marcikiae, M., Mika, A., Mika, B., Primorac, D., Santachiara-Benerecetti, A. S., Cavalli-Sforza, L. L. and Underhill, P. A. (2000). The genetic legacy of Paleolithic Homo sapiens sapiens in extant Europeans: a Y chromosome perspective. Science, 290, 1155–9CrossRef Google Scholar PubMed

Serre, D., Langaney, A., Chech, M., Teschler-Nicola, M., Paunovic, M., Mennecier, P., Hofreiter, M., Possnert, G. G. and Pääbo, S. (2004). No evidence of Neandertal mtDNA contribution to early modern humans. PLoS Biol, 2, 313–17CrossRef Google Scholar PubMed

Serre, D. and Pääbo, S. (2004). Evidence for gradients of human genetic diversity within and among continents. Genome Res, 14, 1679–85CrossRef Google Scholar PubMed

Simoni, L., Calafell, F., Pettener, D., Bertranpetit, J. and Barbujani, G. (2000). Geographic patterns of mtDNA diversity in Europe. Am J Hum Genet, 66, 262–78CrossRef Google Scholar

Soejima, M., Tachida, H., Ishida, T., Sano, A. and Koda, Y. (2006). Evidence for recent positive selection at the human AIM1 locus in a European population. Mol Biol Evol, 23, 179–88CrossRef Google Scholar

Sokal, R. R., Oden, N. L. and Wilson, C. (1991). Genetic evidence for the spread of agriculture in Europe by demic diffusion. Nature, 351, 143–5CrossRef Google Scholar PubMed

Stefansson, H., Helgason, A., Thorleifsson, G., Steinthorsdottir, V., Masson, G., Barnard, J., Baker, A., Jonasdottir, A., Ingason, A., Gudnadottir, V. G., Desnica, N., Hicks, A., Gylfason, A., Gudbjartsson, D. F., Jonsdottir, G. M., Sainz, J., Agnarsson, K., Birgisdottir, B., Ghosh, S., Olafsdottir, A., Cazier, J. B., Kristjansson, K., Frigge, M. L., Thorgeirsson, T. E., Gulcher, J. R., Kong, A. and Stefansson, K. (2005). A common inversion under selection in Europeans. Nat Genet, 37, 129–37CrossRef Google Scholar PubMed

Swallow, D. M. (2003). Genetics of lactase persistence and lactose intolerance. Annu Rev Genet, 37, 197–219CrossRef Google Scholar PubMed

Taberlet, P., Fumagalli, L., Wust-Saucy, A. G. and Cosson, J. F. (1998). Comparative phylogeography and postglacial colonization routes in Europe. Mol Ecol, 7, 453–64CrossRef Google Scholar

Tattersall, I. and Schwartz, J. H. (1999). Hominids and hybrids: the place of Neanderthals in human evolution. Proc Natl Acad Sci USA, 96, 7117–19CrossRef Google Scholar PubMed

The International HapMap Consortium (2003). The International HapMap Project. Nature, 426, 789–96CrossRef

Tishkoff, S. A., Varkonyi, R., Cahinhinan, N., Abbes, S., Argyropoulos, G., Destro-Bisol, G., Drousiotou, A., Dangerfield, B., Lefranc, G., Loiselet, J., Piro, A., Stoneking, M., Tagarelli, A., Tagarelli, G., Touma, E. H., Williams, S. M. and Clark, A. G. (2001). Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science, 293, 455–62CrossRef Google Scholar PubMed

Valladas, H., Joron, J. L., Valladas, G., Arensburg, B., Bar-Yosef, O., Belfer-Cohen, A., Goldberg, P., Laville, H., Meignen, L., Rak, Y., Tchernov, E., Tillier, A. M. and Vandermeersch, B. (1987). Thermoluminescence dates for the Neanderthal burial site at Kebara in Israel. Nature, 330, 159–60CrossRef Google Scholar

Valladas, H., Reyss, J. L., Joron, J. L., Valladas, G., Bar-Yosef, O. and Vandermeersch, B. (1988). Thermoluminescence dating of Mousterian ‘proto-Cro-Magnon’ remains from Israel and the origin of modern man. Nature, 331, 614–16CrossRef Google Scholar

Voight, B. F., Kudaravalli, S., Wen, X. and Pritchard, J. K. (2006). A map of recent positive selection in the human genome. PLoS Biol, 4, e72CrossRef Google Scholar PubMed

Wilson, I. J. and Balding, D. J. (1998). Genealogical inference from microsatellite data. Genetics, 150, 499–510Google Scholar PubMed

Zhivotovsky, L. A., Underhill, P. A., Cinnioglu, C., Kayser, M., Morar, B., Kivisild, T., Scozzari, R., Cruciani, F., Destro-Bisol, G., Spedini, G., Chambers, G. K., Herrera, R. J., Yong, K. K., Gresham, D., Tournev, I., Feldman, M. W. and Kalaydjieva, L. (2004). The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time. Am J Hum Genet, 74, 50–61CrossRef Google Scholar PubMed

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