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Chapter 58 - Transitional Circulation

Published online by Cambridge University Press:  30 November 2019

Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
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Summary

This chapter, provides an overview of the transitional circulation from fetal to neonatal life. The authors describe the physiology of fetal circulation, fetal hemoglobin as well as the changes occurring with transition at birth. Persistent fetal circulation in the setting of a vein of Galen malformation is presented with the relevant anesthetic considerations reviewed.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2019

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References

Suggested Reading

Fuloria, M, Aschner, JL. Persistent pulmonary hypertension of the newborn. Semin Fetal Neonatal Med. 2017;22(4):220–6. PMID: 28342684.CrossRefGoogle ScholarPubMed
Jain, A, McNamara, PJ. Persistent pulmonary hypertension of the newborn: Advances in diagnosis and treatment. Semin Fetal Neonatal Med. 2015;20(4):262–71. PMID: 25843770.CrossRefGoogle ScholarPubMed
Lakshminrusimha, S, Mathew, B, Leach, CL. Pharmacologic strategies in neonatal pulmonary hypertension other than nitric oxide. Semin Perinatol. 2016;40(3):160–73. PMID: 26778236.CrossRefGoogle ScholarPubMed
Puthiyachirakkal, M, Mhanna, MJ. Pathophysiology, management, and outcome of persistent pulmonary hypertension of the newborn: a clinical review. Front Pediatr. 2013;1:23. PMID: 24400269.CrossRefGoogle ScholarPubMed
Stayer, SA, Liu, Y. Pulmonary hypertension of the newborn. Best Pract Res Clin Anaesthesiol. 2010;24(3):375–86. PMID: 21033014.CrossRefGoogle ScholarPubMed
Wu, TW, Azhibekov, T, Seri, I. Transitional hemodynamics in preterm neonates: clinical relevance. Pediatr Neonatol. 2016;57(1):718. PMID: 26482579.CrossRefGoogle ScholarPubMed

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