There are a few underlying principles which, if understood, will reduce the majority, if not all, of a long list of “dos and don'ts” to common sense.

• Consider in advance the work to be undertaken – plan what is needed in terms of chemicals, glassware, movement about the laboratory, and specific training. Include a plan for what to do in the event of something going wrong.

• Consider the risks – are they covered by general good laboratory practice, or are more rigorous controls necessary (e.g., COSHH)?

• Check that you fully understand what you are about to do, and, if not, ask for help. An experienced worker will not complain if asked for instruction, or to observe as you carry out a procedure for the first time (but they will if you injure yourself, others, or cause damage).

• A relaxed atmosphere in a laboratory with lots of activity is a productive and enjoyable place to work, but there is a distinction between this and an environment which is so untidy as to be dangerous. An untidy laboratory is also likely to lead to increased levels of contamination.

• Never work alone, or out of earshot of somebody else. Always work during normal office hours, unless special arrangements have been made for you to be accompanied.

• Take responsibility for your own safety and of those around you. Be aware of all the work taking place in the lab, and warn others immediately if you see something you consider to be dangerous. Breakages and breakdowns of equipment occur regularly in laboratories. Embarrassing as this may be, if you are the cause, do not walk away leaving a hazard for somebody else to find.

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