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Chapter 8 - Mature B-Cell Non-Hodgkin Lymphoma

from Section III - Mature Lymphoid Neoplasm

Published online by Cambridge University Press:  25 November 2023

By
Xiayuan Liang  and
Billie Carstens
Edited by
Silvia Tse Bunting ,
Xiayuan Liang ,
Michele E. Paessler  and
Satheesh Chonat
Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Summary

Non-Hodgkin lymphomas (NHLs) comprise about 10% of all childhood cancers [1]. They include a diverse collection of malignant neoplasms that arise from mature and immature lymphoid cells of B-cell and T-cell origin [1]. Adult and pediatric NHLs have a number of differences, including subtypes, tumor locations, and biologic behaviors, which are summarized in[1]. Morphologic evaluation of adequate tissue, immunophenotyping, and cytogenetic and molecular analysis are essential approaches in the diagnosis of NHLs. This chapter focuses on mature B-cell NHLs in children. Mature T-cell NHLs and immature lymphoid neoplasms are discussed in Chapters 9 and 13.

Type
Chapter
Information
Atlas of Pediatric Hematopathology , pp. 65 - 77
Publisher: Cambridge University Press
Print publication year: 2023

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References

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