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  1. Home
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  3. Biophysics of DNA
  • Cited by 28
Publisher:
Cambridge University Press
Online publication date:
March 2015
Print publication year:
2015
Online ISBN:
9781139542371
DOI:
https://doi.org/10.1017/CBO9781139542371
Subjects:
Life Sciences, Physics and Astronomy, Biological Physics and Soft Matter Physics, Physiology and Biological Physics
Information

Book description

Surveying the last sixty years of research, this book describes the physical properties of DNA in the context of its biological functioning. It is designed to enable both students and researchers of molecular biology, biochemistry and physics to better understand the biophysics of DNA, addressing key questions and facilitating further research. The chapters integrate theoretical and experimental approaches, emphasising throughout the importance of a quantitative knowledge of physical properties in building and analysing models of DNA functioning. For example, the book shows how the relationship between DNA mechanical properties and the sequence specificity of DNA-protein binding can be analyzed quantitatively by using our current knowledge of the physical and structural properties of DNA. Theoretical models and experimental methods in the field are critically considered to enable the reader to engage effectively with the current scientific literature on the physical properties of DNA.

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