Book contents
- Frontmatter
- Contents
- Contributors
- Foreword
- Preface
- Part I General concepts of PET and PET/CT imaging
- Part II Oncologic applications
- Chapter 5 Brain
- Chapter 6 Head, neck, and thyroid
- Chapter 7 Lung and pleura
- Chapter 8 Esophagus
- Chapter 9 Gastrointestinal tract
- Chapter 10 Pancreas and liver
- Chapter 11 Breast
- Chapter 12 Cervix, uterus, and ovary
- Chapter 13 Lymphoma
- Chapter 14 Melanoma
- Chapter 15 Bone
- Chapter 16 Pediatric oncology
- Chapter 17 Malignancy of unknown origin
- Chapter 18 Sarcoma
- Chapter 19 Methodological aspects of therapeutic response evaluation with FDG-PET
- Chapter 20 FDG-PET/CT-guided interventional procedures in oncologic diagnosis
- Index
- References
Chapter 12 - Cervix, uterus, and ovary
from Part II - Oncologic applications
Published online by Cambridge University Press: 05 September 2012
- Frontmatter
- Contents
- Contributors
- Foreword
- Preface
- Part I General concepts of PET and PET/CT imaging
- Part II Oncologic applications
- Chapter 5 Brain
- Chapter 6 Head, neck, and thyroid
- Chapter 7 Lung and pleura
- Chapter 8 Esophagus
- Chapter 9 Gastrointestinal tract
- Chapter 10 Pancreas and liver
- Chapter 11 Breast
- Chapter 12 Cervix, uterus, and ovary
- Chapter 13 Lymphoma
- Chapter 14 Melanoma
- Chapter 15 Bone
- Chapter 16 Pediatric oncology
- Chapter 17 Malignancy of unknown origin
- Chapter 18 Sarcoma
- Chapter 19 Methodological aspects of therapeutic response evaluation with FDG-PET
- Chapter 20 FDG-PET/CT-guided interventional procedures in oncologic diagnosis
- Index
- References
Summary
Introduction
The female genital tract has a complex embryologic origin, tying together elements of the paramesonephric ducts, coelomic epithelium, mesenchyme, and primordial germ cells in an equally intricate physiology, characterized by dramatic changes in function not only over a woman's full life cycle (menarche, pregnancy, and menopause), but with her rapid monthly rhythm of ovulation and menstruation. It should not be surprising that the pathology of this organ system is similarly complex. Tumors of the female pelvis are not only common, but exceedingly varied, including epithelial carcinomas, stromal tumors, sarcomas, and hybrids such as carcinosarcomas. Since these tumors may differ markedly as to FDG avidity, aggressiveness, and route of spread, facile generalizations should be avoided. PET/CT imaging needs to be rigorously correlated with all available clinical and histopathologic information, and with an intimate understanding of the biology of the type of tumor(s) under consideration. The astute PET/CT interpreter also needs to have a clear idea of the clinical purpose of the scan. Is it being performed for initial diagnosis and staging, for therapy planning, or for detection of recurrence? The utility and predictive value of PET may differ in each of these settings, as will be explained in more detail in the case discussions below.
The objectives of this chapter are to furnish the reader with a basic understanding of the range of tumor types affecting each organ, and of the established or emerging role of PET/CT within each clinical context, thus enabling him to derive the maximum amount of information from a given scan. It goes without saying that these principles are to be enlarged from the reader's own fund of experience and personal observation.
- Type
- Chapter
- Information
- A Case-Based Approach to PET/CT in Oncology , pp. 293 - 328Publisher: Cambridge University PressPrint publication year: 2012