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Chapter 3 - Transcriptomic and Epigenomic Approaches for Epilepsy

Published online by Cambridge University Press:  06 January 2023

By
Anika Bongaarts ,
Jagoda Glowacka ,
Konrad Wojdan ,
Angelika Mühlebner ,
Eleonora Aronica  and
James D. Mills
Edited by
Rod C. Scott  and
J. Matthew Mahoney
Rod C. Scott
Affiliation:
University of Vermont
J. Matthew Mahoney
Affiliation:
University of Vermont
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Summary

In the mid-1980s a number of scientists and research bodies conceived the idea of determining the DNA sequence of the entire human genome. Initiated in 1990 and known as the Human Genome Project (HGP), this ambitious, publicly funded project relied on contributions from numerous international laboratories and remains the world’s largest collaborative biological-based project to date. The completion of the HGP thirteen years later in 2003 allowed scientists to view the human genome in its entirety for the first time [1]. It was thought that this would usher in a new age for biological research, allowing for a more comprehensive understanding of complex human diseases and phenotypes. While this was true to an extent, completion of this project led to a series of new, more complicated questions, as is often the case in research.

Type
Chapter
Information
A Complex Systems Approach to Epilepsy
Concept, Practice, and Therapy
 , pp. 19 - 40
Publisher: Cambridge University Press
Print publication year: 2023

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