Skip to main content Accessibility help
×
Hostname: page-component-7479d7b7d-c9gpj Total loading time: 0 Render date: 2024-07-10T00:11:50.462Z Has data issue: false hasContentIssue false

11 - Amplification and Filtering in Biomedical Applications

Published online by Cambridge University Press:  24 December 2019

Muzaffer Ahmad Siddiqi
Affiliation:
Aligarh Muslim University, India
Get access

Summary

Introduction

There has been a lot of development in the use of biomedical equipment for diagnostic and treatment purposes in recent times. A good amount of literature has come from the interdisciplinary area of medical engineering, medical instrumentation, and so on, making medical electronics a specialized field of study. An important constituent of electronics engineering is the study of analog filters. Hence, the design and application of analog filters finds a place in the books and literature on medical engineering and medical instrumentation too. The design of analog filters especially the continuous-time types requires special attention. However, the available books on analog filter design do not adequately relate filter design with biomedical applications. A few simple examples included in this chapter will try to bridge the gap between theoretical design and the application of analog filters in this important field.

We have already studied the basics of continuous-time analog filter in the previous chapters. In this chapter, we will first connect the design of a filter to its utilization in the field of biomedical electronics.

It is a well-known fact that cells in the human body have different element (Na+, K+, Ca++, Cl-) ion concentrations inside and outside the membrane. This difference in ion concentration creates a small electric potential called biopotential. When there is a disturbance in a biopotential, an action potential is generated which is the result of depolarization and repolarization of the cells in the human body. It is the action potential at the location (nodes) on the body which is detectable and can be processed using biomedical circuits. When such signals generated by the heart are collected, it makes up the electrocardiogram (ECG). ECG detectors use electrodes to collect these signals, which are amplified, filtered and displayed for data analysis. ECG signals require filtering and amplification to produce high-quality signals. Not only are different stages of amplification used, specific signal processing is also required. Therefore, instead of a simple (DA) differential amplifier, instrumentation amplifiers (inst-amp) are used. Section 11.2 discusses the the necessity of converting DA into an inst-amp. Transformation of the inst-amp into a biopotential amplifier and as integrated circuit inst-amps especially suitable in medical instruments and devices are discussed in Section 11.3 along with a case study on a piezoelectric transducer.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

[11.1] Prutchi, David and Michael, Norris. 2005. Design and Development of Electronic Instrumentation. New Jersey: Wiley Interscience, John Wiley and Sons Inc., Publication.Google Scholar
[11.2] Kitchin, Charles and Lew, Counts. 2006. ‘Monolithic Instrumentation Amplifier.’ Chapter II and III A in Designer's Guide to Instrumentation Amplifiers. US: Analog Devices.Google Scholar
[11.3] ‘USBPGF-S1. USB Programmable Single Channel Instrumentation Amplifier and Low Pass Filter’. Costa Mesa, CA, US: Alligator Technologies. https://alligatortech.com/downloads/USBPGF-S1_Data_Sheet.pdf.
[11.4] Texas Instruments. 2019. Low Power Instrumentation Amplifier INA 102 Data Sheet. SBOSO27B. US: Burr Brown Corporation.
[11.5] Larsen, Cory. A. 2010. Signal Conditioning Circuitry Design for Instrumentation System. SAND2011-9467. Cal. US: Sandia National Laboratories.Google Scholar
[11.6] Walters, P. L. 2010. Measurement System Engineering. Short Course at Sandia National Laboratory. Cal. US: Sandia National Laboratories.Google Scholar
[11.7] Reyerson, D. E. 1996. Signal Conditioning Primer. Cal. US: Sandia National Laboratories.Google Scholar
[11.8] Texas Instruments. 2011. Filter Pro Users' Guide.
[11.9] Texas Instruments. P O Box 655303, Dallas, Texas 75265 USA. Linear Technology Corporation 1630 McCarthy Blvd, Milpitas, C 95035-7417 (www.linear.com), Maxim Electronics Products and Analog Devices (www.maximintegrated.com/conact). ON Semiconductors P O Box 61312, Phoenix, Arizona85082-1312 USA. (http://onsemi.com). Microchip Technology Incorporated, 2355 West Chandler Blvd, Chandler AZ 85224-6199.
[11.10] Maxim Integrated Products. 2010. Introduction to Electrocardiographs, Tutorial 4693. US: Maxim Integrated Products, Inc.
[11.11] Lee, Shuenn-Yuh, Jia-Hua, Hong, Jin-Ching, Lee, and Qiang, Fang. 2012. ‘An Analog Front- End System with a Low-Power On-Chip Filter and ADC for Portable ECG Detection Devices.’ In Advances in Electro-Cardiogram-Methods and Analysis, edited by Richard, Miller., Germany: IntechOpen.Google Scholar
[11.12] Webster, G. J. 1995. Design of Cardiac Pace Maker. NJ: IEEE Press.Google Scholar
[11.13] Lasanen, K., and J., Lostamovaara. 2005. ‘A 1V Analog Front-end for Detecting QRS Complexes in a Cardiac Signal,’ IEEE Transactions on Circuit Systems 42 (10): 2161–8.Google Scholar
[11.14] Salthouse, C. D., and R., Sarpeshkar. 2003. ‘A Practical Micropower Programmable Band Pass Filter used in Bionic Ears,’ IEEE Journal of Solid-State Circuits 38 (1): 63–70.CrossRefGoogle Scholar
[11.15] Solis-Bustos, Sergio, Jose, Silva-Martinez, Franco, Maloberti, and Edgar, Sanchez-Sinencio. 2000. ‘A 60-dB Dynamic Range CMOS Sixth-Order 2.4-Hz Low Pass Filter for Medical Applications,’ IEEE Transactions on Circuit and Systems-II, Analog and Digital Signal Processing 47 (12): 1391–8.Google Scholar
[11.16] Wang, Kening, Shengqian, Ma, Jing, Feng, Weizhao, Zhang, Manhong, Fan, and Dan, Zhao. 2012. ‘Design of ECG Signal Acquisition System Based on DSP’. SciVerse Science Direct, Procedia Engineering 29: 3763–7.Google Scholar
[11.17] Wang, S., L., Tang, and J. E., Bronlund. 2013. ‘Surface EMG Signal Amplification and Filtering,’ International Journal of Computer Applications 82 (1): 0975–8887.CrossRefGoogle Scholar
[11.18] Shobaki, Mohammed M., Noreha Abdul, Malik, Sheroz, Khan, Anis, Nurashikin, Samnan, Haider, Sofiane, Larbani, Atika, Arshad, and Rumana, Tasnim. 2013. ‘High Quality Acquisition of Surface Electromyography: Conditioning Circuit Design,’ IOP Conference Series: Material Science and Engineering 53: 12027.CrossRefGoogle Scholar
[11.19] Rani, M. S. A., and Wahida B, Mansor. 2009. ‘Detection of Eye Blinks from EEG Signals for Home Lighting Systems,’ Proc. ISMA09. Sharjah, UAE: International Symposium on Mechatronics and Its Applications.Google Scholar
[11.20] Wolpaw, Jonathan R., Niels, Birbaumer, William J., Heetderks, Dennis, J.|McFarland, P., Hunter Peckham, Gerwin, Schalk, Emanuel, Donchin, Louis A., Quatrano, Charles J., Robinson, and Theresa M., Vaughan. 2000. ‘Brain-Computer Interface Technology: A Review of First International Meeting,’ IEEE Transactions on Rehabilitation Engineering 8 (2): 164–173.CrossRefGoogle ScholarPubMed
[11.21] Bhagwati, A. J., and R., Chutia. 2016. ‘Design of Single Channel Portable EEG Signal Acquisition System for Brain Computer Interface Application,’ International Journal of Biomedical Engineering and Science 3 (1): 37–44.Google Scholar
[11.22] Webster, John. G. (ed.). 1992. Medical Instrumentation, Applications and Design, second edition. Mass, US: Houghton Mifflin Co.Google Scholar
[11.23] Langereis, Geert. 2010. Photo-plethysmography (PPG) System, Version 2 (www.semanticscholar. org).
[11.24] Maxim Integrated. 1998. ‘Programmable Universal Filter Implements C-Message Weighting Function,’ Application Note 11. US: Maxim Integrated.

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×