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Chapter 9 - Nonconvulsive Status Epilepticus (NCSE)

from Part II - Case-Based Approach to Specific Conditions

Published online by Cambridge University Press:  22 February 2024

Neville M. Jadeja
Affiliation:
University of Massachusetts Medical School
Kyle C. Rossi
Affiliation:
University of Massachusetts Medical School
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Summary

This chapter describes the diagnosis, types, and management of nonconvulsive status epilepticus using a case-based approach. Generalized status epilepticus including nonconvulsive status epilepticus (NCSE) is a medical emergency that is best managed in an intensive care unit with continuous EEG monitoring. Refractory status epilepticus (RSE) is defined as the failure of seizure activity to terminate despite initial benzodiazepines and additional intravenous antiseizure medications. Refractory status epilepticus is an indication for intravenous anesthetics such as midazolam and propofol with the goal of titrating to burst suppression. Highly epileptiform bursts seen are associated with status epilepticus recurrence despite treatment with intravenous anesthetics, a condition known as super-refractory status epilepticus (SRSE). Additionally, this chapter also describes how to recognize status epilepticus cessation and an uncommon form of NCSE called absence status epilepticus.

Type
Chapter
Information
Critical Care EEG Basics
Rapid Bedside EEG Reading for Acute Care Providers
, pp. 123 - 143
Publisher: Cambridge University Press
Print publication year: 2024

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References

Leitinger, M, Beniczky, S, Rohracher, A, et al. Salzburg consensus criteria for non-convulsive status epilepticus – Approach to clinical application. Epilepsy & Behavior. 2015 Aug 1;49:158–63.Google Scholar
Leitinger, M, Trinka, E, Zimmermann, G, Beniczky, S. Salzburg criteria for nonconvulsive status epilepticus: Details matter. Epilepsia. 2019 Nov;60(11):2334.Google Scholar
Krogstad, MH, Høgenhaven, H, Beier, CP, Krøigård, T. Nonconvulsive status epilepticus: Validating the Salzburg criteria against an expert EEG examiner. Journal of Clinical Neurophysiology. 2019 Mar 1;36(2):141–5.Google Scholar
Trinka, E, Cock, H, Hesdorffer, D, et al. A definition and classification of status epilepticus: Report of the ILAE Task Force on Classification of Status Epilepticus. Epilepsia. 2015 Oct;56(10):1515–23.Google Scholar
Rossetti, AO, Lowenstein, DH. Management of refractory status epilepticus in adults: Still more questions than answers. Lancet Neurology. 2011 Oct 1;10(10):922–30.Google Scholar
Hocker, SE, Britton, JW, Mandrekar, JN, Wijdicks, EF, Rabinstein, AA. Predictors of outcome in refractory status epilepticus. JAMA Neurology. 2013 Jan 1;70(1):72–7.Google Scholar
Phabphal, K, Chisurajinda, S, Somboon, T, Unwongse, K, Geater, A. Does burst suppression achieve seizure control in refractory status epilepticus? BMC Neurology. 2018 Dec;18(1):17.Google Scholar
Das, AS, Lee, JW, Izzy, S, Vaitkevicius, H. Ultra-short burst suppression as a “reset switch” for refractory status epilepticus. Seizure: European Journal of Epilepsy. 2019 Jan 1;64:41–4.CrossRefGoogle ScholarPubMed
Johnson, EL, Martinez, NC, Ritzl, EK. EEG characteristics of successful burst suppression for refractory status epilepticus. Neurocritical Care. 2016 Dec;25(3):407–14.Google Scholar
Thompson, SA, Hantus, S. Highly epileptiform bursts are associated with seizure recurrence. Journal of Clinical Neurophysiology. 2016 Feb 1;33(1):6671.Google Scholar
Panayiotopoulos, CP. Typical absence seizures and their treatment. Archives of Disease in Childhood. 1999 Oct 1;81(4):351–5.CrossRefGoogle ScholarPubMed
Datta, P, Hope, O, Kalamangalam, GP. Teaching NeuroImages: De novo absence status epilepticus in an adult. Neurology. 2016 Apr 26;86(17):e186.Google Scholar

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