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Clobazam

Published online by Cambridge University Press:  01 June 2018

Philip N. Patsalos  and
Erik K. St Louis
Philip N. Patsalos
Affiliation:
UCL Institute for Neurology
Erik K. St Louis
Affiliation:
Mayo Clinic
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The Epilepsy Prescriber's Guide to Antiepileptic Drugs , pp. 41 - 50
Publisher: Cambridge University Press
Print publication year: 2018

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References

Suggested Reading

Anonymous. Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy: Canadian Study Group for Childhood Epilepsy. Epilepsia 1998; 39: 952–959.CrossRefGoogle Scholar
Conry, JA, Ng, YT, Paolicchi, JM, Kernitsky, L, Mitchell, WG, Ritter, FJ, Collins, SD, Tracy, K, Kormany, WN, Abdulnabi, R, Riley, B, Stolle, J. Clobazam in the treatment of Lennox–Gastaut syndrome. Epilepsia 2009; 50: 1158–1166.CrossRefGoogle ScholarPubMed
Feely, M, Gibson, J. Intermittent clobazam for catamenial epilepsy: tolerance avoided. Journal of Neurology, Neurosurgery, and Psychiatry 1984; 47: 1279–1282.CrossRefGoogle ScholarPubMed
Kinoshita, M, Ikeda, A, Begum, T, Terada, K, Shibashaki, H. Efficacy of low-dose, add-on therapy of clobazam (CLB) is produced by its major metabolite, N-desmethyl-CLB. Journal of Neurological Sciences 2007; 263: 44–48.CrossRefGoogle ScholarPubMed
Mechndiratta, MM, Krishnamurthy, M, Rajesh, KN, Singh, G. Clobazam monotherapy in drug naive adult patients with epilepsy. Seizure 2003; 12: 226–228.CrossRefGoogle Scholar
Ng, YT, Collins, SD. Clobazam. Neurotherapeutics 2007; 4: 138–144.CrossRefGoogle ScholarPubMed
Patsalos, PN. Antiepileptic drug interactions – a clinical guide, 3rd edition. Springer, London, UK; 2016.CrossRefGoogle Scholar
Patsalos, PN, Zugman, M, Lake, C, James, A, Ratnaraj, N, Sander, JW. Serum protein binding of 25 antiepileptic drugs in a routine clinical setting: a comparison of free non-protein-bound concentrations. Epilepsia, 2017; 58: 1234–1243.CrossRefGoogle Scholar
Riss, J, Cloyd, J, Gates, J, Collins, S. Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurologica Scandinavica 2008; 118: 69–86.CrossRefGoogle ScholarPubMed
Sennoune, S, Mesdjian, E, Bonneton, J, Genton, P, Dravet, C, Roger, J. Interactions between clobazam and standard antiepileptic drugs in patients with epilepsy. Therapeutic Drug Monitoring 1992; 14: 269–274.CrossRefGoogle ScholarPubMed
Silva, RC, Montenegro, MA, Guerreiro, CA, Guerreiro, MM. Clobazam as add-on therapy in children with epileptic encephalopathy. Canadian Journal of Neurological Sciences 2006; 33: 209–213.CrossRefGoogle ScholarPubMed

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