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Eslicarbazepine acetate

Published online by Cambridge University Press:  04 August 2010

Philip N. Patsalos  and
Blaise F. D. Bourgeois
Philip N. Patsalos
Affiliation:
Chalfont Centre for Epilepsy, Buckinghamshire, UK
Blaise F. D. Bourgeois
Affiliation:
Harvard Medical School, Boston
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The Epilepsy Prescriber's Guide to Antiepileptic Drugs , pp. 59 - 67
Publisher: Cambridge University Press
Print publication year: 2010

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References

Almeida, L, Soares-da-Silva, P.Eslicarbazepine acetate (BIA- 2–093). Neurotherapeutics 2007; 4: 88–96.CrossRefGoogle Scholar
Almeida, L, Falcao, A, Maia, J, Mazur, D, Gellert, M, Soares-da-Silva, P.Single-dose and steady-state pharmacokinetics of eslicarbazepine acetate (BIA 2–093) in healthy elderly and young subjects. Journal of Clinical Pharmacology 2005; 45: 1062–1066.CrossRefGoogle ScholarPubMed
Almeida, L, Potgieter, JH, Maia, J, Potgieter, MA, Moto, F, Soares-da-Silva, P. Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment. European Journal of Clinical Pharmacology 2008; 64: 267–273.CrossRefGoogle ScholarPubMed
Bonifacio, MJ, Sheridan, RD, Parada, A, Cunha, RA, Patmore, L, Soares-da-Silva, P.Interaction of the novel anticonvulsant, BIA 2–093, with voltage-gated sodium channels: Comparison with carbamazepine. Epilepsia 2001; 42: 600–608.CrossRefGoogle ScholarPubMed
Elger, C, Halasz, P, Maia, J, Almeida, L, Soares-da-Silva, P, on behalf of the BIA-2093–301 Investigators Study Group. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: A randomized, double-blind, placebo controlled, parallel-group phase III study. Epilepsia 2009; 50: 454–463.CrossRefGoogle ScholarPubMed
Gil-Nagel, A, Lopes-Lima, J, Almeida, L, Maia, J, Soares-da-Silva, P, on behalf of the BIA-2093–303 Investigators Study Group. Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures. Acta Neurologica Scandinavica 2009; 120: 281–287.CrossRefGoogle ScholarPubMed
Johannessen, Landmark C, Patsalos, PN. Drug interactions involving the new second- and third-generation antiepileptic drugs. Expert Reviews in Neurotherapeutics 2010; 10: 119–140.CrossRefGoogle Scholar
Meis, J, Almeida, L, Falcao, A, Soares, E, Mota, F, Potgieter, MA, Potgieter, JH, Soares-da-Silva, P.Effect of renal impairment on the pharmacokinetics of eslicarbazepine acetate. International Journal of Clinical Pharmacology and Therapeutics 2008; 463: 119–130.Google Scholar
Meis, J, Vaz-de-Silva, M, Almeida, L, Falcao, A, Silveira, P, Guimaraes, S, Graziela, P, Soares-da-Silva, P.Effect of food on the pharmacokinetic profile of eslicarbazepine (BIA 2–093). Drugs R D 2005; 64: 201–206.Google Scholar

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