Guillain Barré syndrome (GBS) is an acquired neuromuscular disorder that presents as rapidly progressive weakness and numbness, usually in an ascending fashion. The underlying pathophysiology is monophasic inflammatory immune-mediated demyelinating polyneuropathy that in many cases is triggered by viral illnesses, usually a few weeks prior to the onset of syndrome. The majority of cases are in young adults, although it can occur in pediatric and elderly age groups. GBS should be considered in the differential diagnosis of new-onset rapidly progressing weakness in an otherwise healthy individual.