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Chapter 9 - Neuropsychologicalassessment of frontotemporal dementia

from Section 3 - Approach to the diagnosis of FTD

Published online by Cambridge University Press:  05 May 2016

Bradford C. Dickerson
Affiliation:
Department of Neurology, Massachusetts General Hospital
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Publisher: Cambridge University Press
Print publication year: 2016

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References

Folstein, MF, Folstein, SE, McHugh, PR. “Mini-mental.” A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189–98.Google Scholar
Mathuranath, PS, Nestor, PJ, Berrios, GE, et al. A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia. Neurology 2000;55(11):1613–20.Google Scholar
Mioshi, E, Dawson, K, Mitchell, J, et al. The Addenbrookes's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening. Int J Geriatr Psychiatry 2006;21:1078–85.Google Scholar
Hsieh, S, Irish, M, Daveson, N, Hodges, JR, Piguet, O. When one loses empathy: its effect on carers of patients with dementia. J Geriatr Psychiatry Neurol 2013;26(3):174–84.Google Scholar
Wechsler, D. Wechsler Adult Intelligent Scale III [Manual], 3rd edn. San Antonio, TX: The Psychological Corporation, 1997.Google Scholar
Golden, CJ. Stroop, Test de Colores y Palabras. Manual de Aplicación Madrid: TEA Ediciones, 1999.Google Scholar
Partington, JE, Leiter, RG. Partington's pathway test. Psychol Serv Bull 1949;1:920.Google Scholar
Conners, CK. Conners’ Continuous Performance Test II: Computer Program for Windows Technical Guide and Software Manual New York: Mutli-Health Systems, 2000.Google Scholar
Torralva, T, Roca, M, Gleichgerrcht, E, et al. A neuropsychological battery of detect specific executive and social cognitive impairments in early frontotemporal dementia. Brain 2009;132:1299–309.Google Scholar
Florance, HV, Stopford, AP, Kalapothakis, JM, et al. Evidence for α-helices in the gas phase: a case study using Melittin from honey bee venom. Analyst 2011;136(17):3446–52.Google Scholar
Collette, F, Amieva, H, Adam, S, et al. Comparison of inhibitory functioning in mild Alzheimer's disease and frontotemporal dementia. Cortex 2007;43(7):866–74.Google Scholar
Hutchinson, AD, Mathias, JL. Neuropsychological deficits in frontotemporal dementia and Alzheimer's disease: a meta-analytic review. J Neurol Neurosurg Psychiatry 2007;78(9):917–28.Google Scholar
Hodges, JR, Davies, R, Xuereb, J, et al. Clinicopathological correlates in frontotemporal dementia. Ann Neurol 2004;56:399406.Google Scholar
Hornberger, M, Savage, S, Hsieh, S, et al. Orbitofrontal dysfunction discriminates behavioral variant frontotemporal dementia from Alzheimer's disease. Dement Geriatr Cogn Disord 2010;30(6):547–52.Google Scholar
Glosser, G, Gallo, JL, Clark, CM, Grossman, M. Memory encoding and retrieval in frontotemporal dementia and Alzheimer's disease. Neuropsychology 2002;16(2):190–6.CrossRefGoogle ScholarPubMed
Kramer, J, Jurik, J, Sha, SJ, et al. Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer's disease. Cogn Behav Neurol 2003;16:211–18.Google Scholar
Rogers, TT, Hocking, J, Noppeney, U, et al. Anterior temporal cortex and semantic memory: reconciling findings from neuropsychology and functional imaging. Cogn Affect Behav Neurosci 2006;6(3):201–13.Google Scholar
Rascovsky, K, Salmon, DP, Hansen, LA, et al. Disparate letter and semantic category fluency deficits in autopsy-confirmed frontotemporal dementia and Alzheimer's disease. Neuropsychology 2007;21(1):2030.Google Scholar
Hou, CE, Miller, BL, Kramer, JH. Patterns of autobiographical memory loss in dementia. Int J Geriatr Psychiatry 2005;20(9):809–15.Google Scholar
Rey, A. L'examen physiologique dans le cas d'encephalopathie traumatique. Arch Psychol (Geneve) 1941;28:286340.Google Scholar
Blackwell, AD, Sahakian, BJ, Vesey, R, et al. Detecting dementia: novel neuropsychological markers of preclinical Alzheimer's disease. Dement Geriatr Cogn Disord 2004;17(1–2):42–8.Google Scholar
Grober, E, Buschke, H, Crystal, H, et al. Screening for dementia by memory testing. Neurology 1988;38:900–3.Google Scholar
Kopelman, MD, Wilson, BA, Baddeley, AD. The autobiographical memory interview: a new assessment of autobiographical and personal semantic memory in amnesic patients. J Clin Exp Neuropsychol 1989;11(5):724–44.Google Scholar
Groot, YC, Wilson, BA, Evans, J, Watson, P. Prospective memory functioning in people with and without brain injury. J Int Neuropsychol Soc 2002;8(5):645–54.Google Scholar
Perri, R, Fadda, L, Caltagirone, C, Carlesimo, GA.Word list and story recall elicit different patterns of memory deficit in patients with Alzheimer's disease, frontotemporal dementia, subcortical ischemic vascular disease, and Lewy body dementia. J Alzheimers Dis 2013;37(1):99107.CrossRefGoogle ScholarPubMed
Lee, AC, Rahman, S, Hodges, JR, et al. Associative and recognition memory for novel objects in dementia: implications for diagnosis. Eur J Neurosci 2003;18(6):1660–70.CrossRefGoogle ScholarPubMed
Sarazin, M, Chauviré, V, Gerardin, E, et al. The amnestic syndrome of hippocampal type in Alzheimer's disease: an MRI study. J Alzheimers Dis 2010; 22(1): 285–94.Google Scholar
Greene, JD, Hodges, JR, Baddeley, AD. Autobiographical memory and executive function in early dementia of Alzheimer type. Neuropsychologia 1995;33(12):1647–70.Google Scholar
Thomas-Antérion, C, Jacquin, K, Laurent, B. Differential mechanisms of impairment of remote memory in Alzheimer's and frontotemporal dementia. Dement Geriatr Cogn Disord 2000;11(2):100–6.Google Scholar
Kamminga, J, O'Callaghan, C, Hodges, JR, Irish, M. Differential prospective memory profiles in frontotemporal dementia syndromes. J Alzheimers Dis 2014;38(3):669–79.Google Scholar
Gasparini, MA. Descriptive study on constructional impairment in frontotemporal dementia and Alzheimer´s disease. Eur J Neurol 2008;15:589–97.Google Scholar
Possin, KL, Laluz, VR, Alcantar, OZ, et al. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia. Neuropsychologia 2011;49:43–8.Google Scholar
Osterrieth, PA.File test de copie d' une figure complex: Contribution al'etude de la perception et de la memoire [The test of copying a complex figure: a contribution to the study of perception and memory].” Arch Psychol (Geneve) 1944;30:286356.Google Scholar
Warrington, EK, James, M. The Visual Object and Space Perception Battery Bury St Edmunds, England: Thames Valley Test Company, 1991.Google Scholar
Clague, F, Dudas, RB, Thompson, SA, et al. Multidimensional measures of person knowledge and spatial associative learning: can these be applied to the differentiation of Alzheimer's disease from frontotemporal and vascular dementia? Neuropsychologia 2005;43(9):1338–50.Google Scholar
Possin, KL, Feigenbaum, D, Rankin, KP, et al. Dissociable executive functions in behavioral variant frontotemporal and Alzheimer dementias. Neurology 2013;80(24):2180–5.Google Scholar
Pose, M, Cetkovich, M, Gleichgerrcht, E, et al. The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood. Int Rev Psychiatry 2013;25(2):159–67.Google Scholar
Dubois, B, Slachevsky, A, Litvan, I, Pillon, B. The FAB: a Frontal Assessment Battery at bedside. Neurology 2000;55(11):1621–6.Google Scholar
Torralva, T, Roca, M, Gleichgerrcht, E, et al. INECO Frontal Screening (IFS): a brief, sensitive, and specific tool to assess executive functions in dementia. J Int Neuropsychol Soc 2009;15(5):777–86.CrossRefGoogle ScholarPubMed
Kleinhans, N, Akshoomoff, N, Delis, DC. Executive functions in autism and Asperger's disorder: flexibility, fluency, and inhibition. Dev Neuropsychol 2005;27(3):379401.CrossRefGoogle ScholarPubMed
Nelson, H. A modified card sorting response sensitive to frontal lobe defects. Cortex 1976;12:313–24.Google Scholar
Cullbertson, WC, Zillmer, EA. Tower of London. Technical Manual, 2nd edn. Toronto, Drexel University: Multi-Health System Inc., 2005.Google Scholar
Burgess, PW, Shallice, T. The Hayling Test and Brixton Tests Thurston, Suffolk: Thames Valley Test Company, 1997.Google Scholar
Delis, DC, Kaplan, E, Kramer, JH. The Delis-Kaplan Executive Function System San Antonio, TX: The Psychological Corporation, 2001.Google Scholar
Harciarek, M, Cosentino, S. Language, executive function and social cognition in the diagnosis of frontotemporal dementia syndromes. Int Rev Psychiatry 2013;25(2):178–96.Google Scholar
Ringman, JM, Kwon, E, Flores, DL, et al. The use of profanity during letter fluency tasks in frontotemporal dementia and Alzheimer disease. Cogn Behav Neurol 2010;23(3):159–64.Google Scholar
Davis, C, Heidler-Gary, J, Gottesman, RF, et al. Action versus animal naming fluency in subcortical dementia, frontal dementias, and Alzheimer's disease. Neurocase 2010;16(3):259–66.Google Scholar
Libon, DJ, Xie, SX, Moore, P, et al. Patterns of neuropsychological impairment in frontotemporal dementia. Neurology 2007;68(5):369–75.Google Scholar
Hornberger, M, Piguet, O, Kipps, C, Hodges, JR. Executive function in progressive and nonprogressive behavioral variant frontotemporal dementia. Neurology 2008;71:1481–8.CrossRefGoogle ScholarPubMed
Shallice, T. Specific impairments of planning. Philos Trans R Soc Lond B Biol Sci 1982;298(1089):199209.Google Scholar
Possin, KL, Chester, SK, Laluz, V, et al. The frontal-anatomic specificity of design fluency repetitions and their diagnostic relevance for behavioral variant frontotemporal dementia. J Int Neuropsychol Soc 2012;18(5):834–44.Google Scholar
Torralva, T, Kipp, CM, Hodges, JR, et al. The relationship between affective decision-making and theory of mind in the frontal variant of frontotemporal dementia. Neuropsychologia 2007;45:342–9.Google Scholar
Gregory, C, Lough, S, Stone, VE, et al. Theory of mind in frontotemporal dementia and Alzheimer's disease: theoretical and practical implications. Brain 2002;125:752–64.Google Scholar
Stone, VE, Baron-Cohen, S, Knight, RT. Frontal lobe contributions to theory of mind. J Cogn Neurosci 1998;10:640–56.Google Scholar
Baron-Cohen, S, Jolliffe, T, Mortimore, C, Robertson, M. A further advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger syndrome. J Child Psychol Psychiatry 1997;38:813–22.Google Scholar
Golan, O, Baron-Cohen, S, Hill, J. The Cambridge Mindreading (CAM) face-voice battery: testing complex emotion recognition in adults with and without Asperger syndrome. J Autism Dev Disord 2006;36(2):169–83.Google Scholar
Baron-Cohen, S, Jolliffe, T, Mortimore, C, Robertson, M. Another advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger Syndrome. J Child Psychol Psychiatry 1997;38:813–22.Google Scholar
Perner, J, Wimmer, H. ‘‘John thinks that Mary thinks that’’ attribution of second-order false beliefs by 5- to 10-year-old children. J Exp Child Psychol 1985;39:437–71.Google Scholar
Freedman, M, Binns, MA, Black, SE, et al. Theory of mind and recognition of facial emotion in dementia: challenge to current concepts. Alzheimer Dis Assoc Disord 2013;27(1):5661.Google Scholar
Fernandez-Duque, D, Baird, JA, Black, SE. False-belief understanding in frontotemporal dementia and Alzheimer's disease. J Clin Exp Neuropsychol 2009;31(4):489–97.Google Scholar
Lough, S, Kipps, CM, Treise, C et al. Social reasoning, emotion and empathy in frontotemporal dementia. Neuropsychologia 2006;44(6):950–8.Google Scholar
Happe, FG. An advanced test of theory of mind: Understanding of story characters’ thoughts and feelings by able autistic, mentally handicapped, and normal children and adults. J Autism Dev Disord 1994;24:129–54.Google Scholar
McDonald, S, Bornhofen, C, Shum, D, et al. Reliability and validity of The Awareness of Social Inference Test (TASIT): a clinical test of social perception. Disabil Rehabil 2006;28:1529–42.Google Scholar
Ekman, P, Friesen, E. Pictures of Facial Affects Palo Alto, CA: Consulting Psychologists Press, 1976Google Scholar
Young, AW, Rowland, D, Calder, AJ, et al. Facial expression megamix: tests of dimensional and category accounts of emotion recognition. Cognition 1997;63:271313.CrossRefGoogle ScholarPubMed
Davis, MH. Measuring individual differences in empathy. Evidence for multidimensional approach. J Pers Soc Psychol 1993;44:113–26.Google Scholar
Savage, SA, Lillo, P, Kumfor, F, et al. Emotion processing deficits distinguish pure amyotrophic lateral sclerosis from frontotemporal dementia. Amyotroph Lateral Scler Frontotemporal Degener 2014;15(1–2):3946.Google Scholar
Rankin, KP, Gorno-Tempini, ML, Allison, SC, et al. Structural anatomy of empathy in neurodegenerative disease. Brain 2006;129:2945–56.CrossRefGoogle ScholarPubMed
Kipps, CM, Nestor, PJ, Acosta-Cabronero, J, et al. Understanding social dysfunction in the behavioural variant of frontotemporal dementia: the role of emotion and sarcasm processing. Brain 2009;132:592603.Google Scholar
Kumfor, F, Piguet, O. Disturbance of emotion processing in frontotemporal dementia: a synthesis of cognitive and neuroimaging findings. Neuropsychol Rev 2012;22(3):280–97.Google Scholar
Diehl-Schmid, J, Pohl, C, Ruprecht, C, et al. The Ekman 60 Faces Test as a diagnostic instrument in frontotemporal dementia. Arch Clin Neuropsychol 2007;22(4):459–64.Google Scholar
Perry, RJ, Rosen, HR, Kramer, JH, et al. Hemispheric dominance for emotions, empathy and social behaviours: evidence from right and left handers with frontotemporal dementia. Neurocase 2001;7:145–60.Google Scholar
Gleichgerrcht, E, Torralva, T, Roca, M, et al. The role of social cognition in moral judgment in frontotemporal dementia. Soc Neurosci 2010;6(2):113–22.Google ScholarPubMed
Burgess, P. Development of a simplified version of the multiple errands test for use in hospital settings. Neuropsychol Rehabil 2002;12:231–55.Google Scholar
Manly, T, Hawkins, K, Evans, J, et al. Rehabilitation of executive function: facilitation of effective goal management on complex tasks using periodic auditory alerts. Neuropsychologia 2002;40(3):271–81.CrossRefGoogle ScholarPubMed
Bechara, A, Damasio, AR, Damasio, H, Anderson, SW. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 1994;50(1–3):715.Google Scholar
Funkiewiez, A, Bertoux, M, de Souza, LC, et al. The SEA (Social cognition and Emotional Assessment): a clinical neuropsychological tool for early diagnosis of frontal variant of frontotemporal lobar degeneration. Neuropsychology 2012;26(1):8190.Google Scholar
Bertoux, M, Delavest, M, de Souza, LC, et al. Social Cognition and Emotional Assessment differentiates frontotemporal dementia from depression. J Neurol Neurosurg Psychiatry 2012;83(4):411–16.Google Scholar
Gorno-Tempini, ML, Hillis, AE, Weintraub, S, et al. Classification of primary progressive aphasia and its variants. Neurology 2011;76(11):1006–14.Google Scholar
Bonner, MF, Ash, S, Grossman, M. The new classification of primary progressive aphasia into semantic, logopenic, or nonfluent/agrammatic variants. Curr Neurol Neurosci Rep 2010;10(6):484–90.Google Scholar
Patterson, K, Hodges, JR. Disorders of semantic memory. In Baddleley, A., Wilson, B., Watts, F. eds. Handbook of Memory Disorders Chichester: John Wiley. 1995;167–86.Google Scholar
Howard, D, Patterson, K. Pyramids and Palm Trees: A Test of Semantic Access from Words and Pictures Bury St Edmunds, Suffolk: Thames Valley Test Company, 1992.Google Scholar
Adlam, AL, Patterson, K, Bozeat, S, Hodges, JR. The Cambridge Semantic Memory Test Battery: detection of semantic deficits in semantic dementia and Alzheimer's disease. Neurocase 2010;16(3):193207.Google Scholar
Hodges, JR, Martinos, M, Woollams, AM, et al. Repeat and Point: differentiating semantic dementia from progressive non-fluent aphasia. Cortex 2008;44(9):1265–70.Google Scholar
Bak, TH, Hodges, JR. Kissing and dancing – a test to distinguish the lexical and conceptual contributions to noun/verb and action/object dissociation. Preliminary results in patients with frontotemporal dementia. J Neurolinguist 2003;16(2–3):169–81.Google Scholar
Kay, J, Lesser, R, Coltheart, M. PALPA – Psycholinguistic Assessments of Language Processing in Aphasia Hove (East Sussex): Psychology Press (Taylor & Francis Group), 1992.Google Scholar
Rogers, TT, Patterson, K, Graham, K. Colour knowledge in semantic dementia: it is not all black and white. Neuropsychologia 2007;45:3285–98.Google Scholar
Peelle, JE, Cooke, A, Moore, P, Vesely, L, Grossman, M. Syntactic and thematic components of sentence processing in progressive nonfluent aphasia and nonaphasic frontotemporal dementia. J Neurolinguist 2007;20:482–94.Google Scholar
Lezak, MD, Howieson, DB, Loring, DW. Neuropsychological Assessment New York: Oxford University Press, 2004.Google Scholar
Hodges, JR, Graham, N, Patterson, K. Charting the progression in semantic dementia: implications for the organization of semantic memory. Memory 1995;3(3–4):463–95.Google Scholar
Breedin, S, Saffran, E, Coslett, H. Reversal of the concreteness effect in a patient with semantic dementia. Cogn Neuropsychol 1994;11:617–60.Google Scholar
Hoffman, P, Jones, RW, Lambon Ralph, MA. Be concrete to be comprehended: consistent imageability effects in semantic dementia for nouns, verbs, synonyms and associates. Cortex 2013;49:1206–18.Google Scholar
Kaplan, E, Googlass, H, Weintraub, S. Boston Naming Test Philadelphia: Lea & Febiger, 1983.Google Scholar
Harciarek, M, Kertesz, A. Primary progressive aphasias and their contribution to the contemporary knowledge about the brain-language relationship. Neuropsychol Rev 2011;21(3):271–87.Google Scholar
Jefferies, E, Lambon Ralph, MA, Jones, R, Bateman, D, Patterson, K. Surface dyslexia in semantic dementia: a comparison of the influence of consistency and regularity. Neurocase 2004;20(4):290–9.Google Scholar
Patterson, K, Lambon Ralph, MA, Jefferies, E, et al. ‘Pre-semantic’ cognition in semantic dementia: six deficits in search of an explanation. J Cogn Neurosci 2006;16:169–83.Google Scholar
Woollams, AM, Lambon Ralph, MA, Plaut, DC, Patterson, K. SD-squared: on the association between semantic dementia and surface dyslexia. Psychol Rev 2007;114(2):316–39.Google Scholar
Goodglass, H, Kaplan, E. Assessment of Aphasia and Related Disorders Philadelphia: Lea & Febiger, 1976.Google Scholar
Meteyard, L, Quinn, E, Patterson, K. Ever decreasing circles: speech production in semantic dementia. Cortex 2014;55:1729.Google Scholar
Gorno-Tempini, ML, Brambati, SM, Ginex, V, et al. The logopenic/phonological variant of primary progressive aphasia. Neurology 2008;71:1227–34.Google Scholar

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