In this concluding chapter, we evaluate our framework and reflect on the core questions we set out in the introductory chapter. First, we summarize the main conceptual contributions of our framework and its ability to specify and operationalize the interdependence between institutions and technologies, and its implications for the provision of expected services. The main building blocks of our comprehensive framework comprise the identification of critical functions, the interdependent dimensions of institutions and technologies, and the modalities of their alignment. Second, we reflect on the empirical cases detailed in the second part of the book, in order to learn lessons about what we gained from our framework when dealing with “real world” situations and potential ways that the framework could be improved. Through the variety of cases we selected, these empirical explorations showed the capacity of our framework to identify and analyze characteristics and difficulties proper to the network infrastructures investigated. Finally, we consider how our approach can provide guidance for public policy and private sector initiatives against the background of ongoing transitions in network infrastructures. We explore how the issues of coordination and alignment could be managed by private agents (consumers, firms, and other organizations) as well as public authorities.