This volume demonstrates the value of interactions between neurology and the basic sciences that underpin it. The text considers a range of topics from the points of view of both neurobiologist and clinician and reveals how advances in our understanding are made. The selected topics cover a wide range of levels of organization in the nervous system. For each one, distinguished researchers from around the world make contributions, including general reviews of normal and pathological mechanisms as well as detailed accounts of the basic processes involved. The book's coverage boasts an excellent section on the physiology and pathophysiology of central and peripheral nerve fibres. Also of particular note are the chapters on neuronal plasticity, cell death and axonal regeneration. The book is dedicated to Tom Sears, who at the time of its original publication was retiring as Professor at London's Institute of Neurology (Queen Square).

"...a valuable read as it projects an immediate overview and understanding of key membrane and molecular events involved in axonal conductions and mechanisms of neural control and neural viability in health and disease." Roger N. Rosenberg, Archives of Neurology

"...this is a well-written, adequately illustrated, and generally interesting textbook that will be found a useful resource for neuroscientists of all different specialties." Martin Bettag, Neurosurgery Review