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Chapter 10 - Myopathies and the Parturient

Published online by Cambridge University Press:  26 January 2024

David R. Gambling
Affiliation:
University of California, San Diego
M. Joanne Douglas
Affiliation:
University of British Columbia, Vancouver
Grace Lim
Affiliation:
University of Pittsburgh
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Summary

Myopathies are a group of clinical diseases that impair the function of skeletal muscle. The muscle fibers are affected directly, as the innervation and neuromuscular junctions remain intact. Although a primary symptom is often weakness, variable patterns of stiffness, contractures, or cramping may also be present. These symptoms are often exacerbated by the physiologic stress of pregnancy and labor, which may unmask a previously undiagnosed myopathy. The hereditary myopathies include muscular dystrophies, congenital myopathies, metabolic myopathies, and disorders of muscle membrane excitability. Inflammatory myopathies are a subset of acquired myopathy. Each classification has specific obstetric and anesthetic considerations, which will be described in detail.

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Publisher: Cambridge University Press
Print publication year: 2024

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