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Case 19 - Pulmonary alveolar proteinosis

Published online by Cambridge University Press:  07 October 2011

By
David Levin  and
Thomas Hartman
Edited by
Thomas Hartman
Thomas Hartman
Affiliation:
Mayo Clinic, Rochester
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Summary

Imaging description

The classic appearance of pulmonary alveolar proteinosis is symmetric, predominately perihilar, ground-glass opacity with intralobular linear opacities and interlobular septal thickening (“crazy-paving” pattern) [1–3] (Figures 19.1–19.4). There is often geographic sparing of secondary lobules and periphery of the lung. Consolidation can be seen in advanced cases.

Importance

Pulmonary alveolar proteinosis is one of several conditions associated with a crazy-paving pattern on high-resolution CT. Knowledge of the different causes of this pattern can aid in preventing diagnostic errors [3].

Type
Chapter
Information
Pearls and Pitfalls in Thoracic Imaging
Variants and Other Difficult Diagnoses
 , pp. 50 - 51
Publisher: Cambridge University Press
Print publication year: 2011

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References

Holbert, JMCostello, PLi, WHoffman, RMRogers, RM.CT features of pulmonary alveolar proteinosisAJR Am J Roentgenol 2001 176 1287CrossRefGoogle ScholarPubMed
Chung, MJLee, KSFranquet, TMetabolic lung disease: imaging and histopathologic findingsEur J Radiol 2005 54 233CrossRefGoogle ScholarPubMed
Rossi, SEErasmus, JJVolpacchio, M“Crazy-paving” pattern at thin-section CT of the lungs: radiologic-pathologic overviewRadiographics 2003 23 1509CrossRefGoogle ScholarPubMed

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