Muscular development starts around day 17 of embryogenesis following the formation of the three germ layers – ectoderm, entoderm, and mesoderm. Bones and skeletal muscle both originate from the mesoderm. The mesoderm is composed of four parts: the chordamesoderm, the paraxial mesoderm, the intermediate mesoderm, and the lateral mesodermal plate. Skeletal muscle cells originate from the paraxial mesoderm by forming a group of cells called somites first, then dermomyotome, and finally the myotome [1]. The chordamesoderm is the progenitor of the notochord, while paraxial mesoderm forms cranial mesoderm (from which skeletal muscles of the face and cranium develop) and somites of the trunk [1, 2].