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Chapter 1.3 - Chapter

from 1 - Inflammatory Conditions

Published online by Cambridge University Press:  06 October 2022

Anita Arsovska
Affiliation:
University of Ss Cyril and Methodius
Derya Uluduz
Affiliation:
Istanbul Üniversitesi
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Summary

Inflammatory Bowel Diseases (IBD) are idiopathic, chronic inflammatory diseases of the intestinal system. Common types of vasculitides that are associated with IBD are: Large Vessel Vasculitis, mainly Takayasu Arteritis, Cutaneous Vasculitis, Anti – Neutrophil Cytoplasmic Antibody (ANCA) – Associated Vasculitides (AAV), mostly Granulomatosis with Polyangiitis (GPA) and Central Nervous System Vasculitis. Symptoms are related to bowel ischemia due to mesenteric vessel involvement or gastrointestinal ulcers due to small vessel involvement. Etiological investigations constitute; microbiologic tests to exclude super – infections (Stool microscopy, culture, Entamoeba Antigen Testing, C difficile toxin a&b, CMV – DNA, Tuberculosis, etc), renal function evaluation and endoscopy. Endoscoy reveals focal (discontinuous) granular pattern over mild mucosal inflammation that may lead to difficulty in discriminating ulcerative cholitis from Chrons Disease at initial colonoscopy. Vasculitis related ulcers are usually multiple, irregular and uneven based. For the treatment of combined disease, most cases require steroids or biologic agents. Pulse steroid, cyclophosphamide, rituximab or surgical treatment was necessary for the management. Angiographic revascularization may be necessary to the stenotic mesenteric vasculature

Type
Chapter
Information
Rare Causes of Stroke
A Handbook
, pp. 92 - 98
Publisher: Cambridge University Press
Print publication year: 2022

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References

Sy, A, Khalidi, N, Dehghan, N, et al. Vasculitis in patients with inflammatory bowel diseases: A study of 32 patients and systematic review of the literature. Semin Arthritis Rheum. 2016;45(4): 475482.CrossRefGoogle ScholarPubMed
Kilic, L, Kalyoncu, U, Karadag, O, et al. Inflammatory bowel diseases and Takayasu’s arteritis: coincidence or association? Int J Rheum Dis. 2016;19(8): 814818.Google Scholar
Akiyama, S, Fujii, T, Matsuoka, K, et al. Endoscopic features and genetic background of inflammatory bowel disease complicated with Takayasu arteritis. J Gastroenterol Hepatol. 2017;32(5): 10111017.Google Scholar
Anderson, E, Gakhar, N, Stull, C, Caplan, L. Gastrointestinal and Hepatic Disease in Vasculitis. Rheum Dis Clin North Am. 2018;44(1): 114.Google Scholar
Hatemi, I, Hatemi, G, Çelik, AF. Systemic vasculitis and the gut. Curr Opin Rheumatol. 2017;29(1): 3338.Google Scholar

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  • Chapter
  • Edited by Derya Uluduz, Istanbul Üniversitesi
  • Anita Arsovska
  • Book: Rare Causes of Stroke
  • Online publication: 06 October 2022
  • Chapter DOI: https://doi.org/10.1017/9781108902793.017
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  • Chapter
  • Edited by Derya Uluduz, Istanbul Üniversitesi
  • Anita Arsovska
  • Book: Rare Causes of Stroke
  • Online publication: 06 October 2022
  • Chapter DOI: https://doi.org/10.1017/9781108902793.017
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Chapter
  • Edited by Derya Uluduz, Istanbul Üniversitesi
  • Anita Arsovska
  • Book: Rare Causes of Stroke
  • Online publication: 06 October 2022
  • Chapter DOI: https://doi.org/10.1017/9781108902793.017
Available formats
×