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Neurophysiological disturbances of cognitive processing in Alzheimer and multi-infarct dementia. An evoked potential study

Published online by Cambridge University Press:  18 September 2015

E.J. Colon
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Summary

Disturbances in information processing can be established by means of evoked potentials (EP). Sensory information is transported over the white myelinated fibers towards the brain. Classification and storage will take place in the cortical grey. This kind of information processing can be made visible by means of EP's.

In 9 patients with dementia. Alzheimer's type and 7 patients with multi-infarct dementia a delay in information processing has been established by means of EP's. In multi-infarct dementia also a delay in short latency components was determined. The generators of various parts of the information processing in the cerebral cortex have been delayed and distorted. We speculate that, beside loss of neurons in the cerebral cortex, an alteration in cortical glial cells might be the cause of some disturbances in patients with dementia.

Keywords

Alzheimer's dementiamulti-infarct dementiaevoked potentialsinformation processingDementieEvoked PotentialsAlzheimer dementieMulti-infarct dementie
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 6 , Issue 4 , December 1994 , pp. 69 - 73
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1994

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References

Literatuur

1.Katchaturian, Z.Progress of research of Alzheimer's disease. In Hutton, JT, Kenny, AD, red. Senile Dementia of the Alzheimer type. New York: Alan Liss 1985;379–384.Google Scholar
2.Cutler, NR.Utility of biologic markers in the evaluation and diagnosis of Alzheimer's disease. Brain Dysfunction 1988;1:12–31.Google Scholar
3.Small, GW, Greenberg, DA.Biologic markers, genetics and Alzheimer's disease. Arch gen Psychiat 1988;45:945–7.CrossRefGoogle ScholarPubMed
4.Thal, LJ.Dementia update: diagnosis and neuropsychiatric aspects. J clin Psychiatry 1988; 49 (suppl): 5–7.Google ScholarPubMed
5.Boller, FO, Lopez, FOL, Moossy, J.Diagnosis of dementia: clinico-pathologic correlations. Neurology 1989;39:76.CrossRefGoogle Scholar
6.Garber, HJ, Weilburg, JB, Manschreck, TC.Clinical use of topographic brain mapping in psychiatry. J clin Psychiatry 1989;50:205–11.Google ScholarPubMed
7.Martin-Loechs, M, Gil, P, Rubia, FJ.Two-Hz Wide EEG Bands in Alzheimer's Disease. Biol Psychiat 1993;33:153–9.CrossRefGoogle Scholar
8.Saletu, B, Anderer, P, Fischhof, PK, et al.EEG mapping and psychopharmacological studies with denbufylline in SDAT and MID. Biol Psychiat 1992;32:668–81.CrossRefGoogle ScholarPubMed
9.Celesia, G.EEG and event related potentials in aging and dementia. J clin Neurophysiol 1986;3:99–111.CrossRefGoogle ScholarPubMed
10.Goodin, DS, Aminoff, MJ.Evaluation of dementia by event-related potentials. J clin Neurophysiol 1992;9,4:521–5.CrossRefGoogle ScholarPubMed
11.Patterson, JV, Michalewski, HJ, Starr, A.Latency variability of the Components of Auditory Event-related Potentials to infrequent stimuli in aging, Alzheimer-type Dementia and Depression. EEG clin Neurophysiol 1989;71:450–60.Google Scholar
12.Pollock, VE, Schneider, LS, Chui, HC, Henderson, V, Zemansky, M, Sloane, RB.Visual evoked potentials in dementia: A meta-analysis and empirical study of Alzheimer's disease patients. Biol Psychiat 1989;25:1003–13.CrossRefGoogle ScholarPubMed
13.Colon, EJ, De Weerd, A.Long-latency somatosensory evoked potentials. J clin Neurophysiol 1986;3:279–96.CrossRefGoogle ScholarPubMed
14.Leys, D, Soetaert, G, Petit, H, Faugette, A, Pruvo, J, Steinling, M.Periventricular and white matter magnetic resonance imaging hyperintensities do not differ between Alzheimer's disease and normal ageing. Arch Neurol 1990;47:524–7.CrossRefGoogle ScholarPubMed
15.Kalayam, B, Shamoian, CA.Geriatric psychiatry: an update. J clin Psychiatry 1990;51:177–83.Google ScholarPubMed
16.Abbruzzesse, G, Reni, L, Cocito, L, Ratto, S, Abbruzzesse, M, Favale, E.Short-latency somatosensory evoked potentials in degenerative and vascular dementia. J Neurol Neurosurg- Psychiat 1984; 47:1034–7.CrossRefGoogle Scholar
17.Allest, D' AM, Laguet, P, Raimbout, J.Visual and somesthetic potentials in neurolipidosis. In Courjon, J, Mauguiere, J, Revol, M, red. Clinical applications of evoked potentials in neurology, New York: Raven Press 1985;397–407.Google Scholar
18.Oepen, G, Doerr, M, Thoden, U; Visual and somatosensory evoked potentials in huntington's chorea. Electroencephalogr clin Neurophysiol 1981;51:666–70.CrossRefGoogle ScholarPubMed
19.Colon, EJ.The cerebral cortex in presenile dementia. Acta Neuropath (Berl) 1973;23:281–90.CrossRefGoogle ScholarPubMed
20.Roberts, WR, Leigh, PN, Weinberger, DR.Neuropsychiatric disorders. Londen: Wolfe Publ, 1993: Chpt 2, page 14.Google Scholar
21.Colon, EJ.Quantitative cytoarchitectonics of the human cerebral cortex. Psychiat Neurol Neurochir 1971;74:291–302.Google ScholarPubMed
22.Goodman, R.Neural misconnections and psychiatric disorders. Is there a link? Am J Psychiat 1989;154:292–9.Google Scholar
23.Delacourte, A.General and dramatic glial reaction in Alzheimer brains. Neurology 1990;40:33–37.CrossRefGoogle ScholarPubMed
24.Kemper, T.Neuroanatomical and neuropathological changes in normal ageing and dementia. In Albert, ML, red. Clinical Neurology of Ageing, New York: Oxford Univ Press 1984;9–52.Google Scholar
25.Polich, J.On the clinical application of P300. Biol Psychiat 1992;31:647–9.Google ScholarPubMed