Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-23T00:33:49.588Z Has data issue: false hasContentIssue false
  • English
  • Français

Association of demographic, lifestyle factors and serum biomarkers with hypertension in elderly Chinese people

Published online by Cambridge University Press:  06 January 2016

XIUQIN HONG ,
NUALNONG WONGTONGKAM ,
PAUL RUSSELL WARD ,
SHUIYUAN XIAIO ,
SHULING WANG ,
QIAN PENG ,
QI ZUO ,
DAN ZENG ,
JIA WANG  and
CHENXU WANG
XIUQIN HONG
Affiliation:
School of Public Health, Central South University, Changsha, China.
NUALNONG WONGTONGKAM*
Affiliation:
School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW, Australia.
PAUL RUSSELL WARD
Affiliation:
School of Health Sciences, Faculty of Medicine, Nursing and Health Sciences, Flinders University, Adelaide, Australia.
SHUIYUAN XIAIO
Affiliation:
Center for Global Health, Central South University, Changsha, China.
SHULING WANG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
QIAN PENG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
QI ZUO
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
DAN ZENG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
JIA WANG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
CHENXU WANG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
*
Address for correspondence: Nualnong Wongtongkam, School of Biomedical Sciences, Charles Sturt University, 1448-Building, Bathurst, NSW 2795, Australia E-mail: nwongtongkam@csu.edu.au
Get access Rights & Permissions [Opens in a new window]

Abstract

Hypertension is a major cause of premature death in China. Understanding risk factors including behavioural and predisposing factors may help to prevent development of hypertension and control the extent of premature mortality. In this case-control design conducted in Hunan province, 416 hypertensive subjects were matched with an equal number of normotensive persons from nearly 9,000 volunteers. A self-report questionnaire was employed to collect demographic and lifestyle information, and fasting serum biomarkers related to lipid profile, renal function, glucose level and uric acid were assessed. When age and sex were stratified, serum biomarkers such as blood urea nitrogen and triglycerides showed a significant difference for hypertension, while lifestyle behaviours including university degree, alcohol use, Body Mass Index and psychological stress (job and married life) were also associated with hypertension. After adjusting for covariate confounding factors, only elevated triglyceride levels were strongly linked to high blood pressure, odds ratio = 1.55, 95 per cent confidence level = 1.16–2.06. To control high blood pressure, hypertriglyceridemia should be included in hypertension treatment and followed up to assess the substantial risk of cardiovascular diseases.

Keywords

case-controlChinahypertensionlifestyleserum biomarkerstriglyceride
Type
Articles
Information
Ageing & Society , Volume 37 , Issue 4 , April 2017 , pp. 661 - 674
Copyright
Copyright © Cambridge University Press 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cheng, T. O. 2005. Rising cholesterol levels in China. International Journal of Cardiology, 105, 3, 332–3.Google Scholar
Cheng, T. O. 2006. Effects of fast foods, rising blood pressure and increasing serum cholesterol on cardiovascular disease in China. American Journal of Cardiology, 97, 11, 1676–8.Google Scholar
China Population and Development Research Center 2012. People's University of China. Haidian District, Beijing, China. Available online at http://www.cpdrc.org.cn. [10 February 2015].Google Scholar
Chinese Nutrition Society, National Institute of Nutrition and Food Safety of China CDC, 2007. Dietary Guidelines for Chinese Residents. Available online at http://www.cnsoc.org/cn/nutrition. [12 February 2015].Google Scholar
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L. Jr, Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T. Jr, Roccella, E. J. 2003. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA: The Journal of the American Medical Association, 289, 19, 2560–72.Google Scholar
Cui, Z., Huxley, R., Wu, Y. and Dibley, M. J. 2010. Temporal trends in overweight and obesity of children and adolescents from nine provinces in China from 1991–2006. International Journal of Pediatric Obesity, 5, 5, 365–74.Google Scholar
French, S. A., Harnack, L. and Jeffery, R. W. 2000. Fast food restaurant use among women in the Pound of Prevention study: dietary, behavioral and demographic correlates. International Journal of Obesity and Related Metabolic Disorders, 24, 10, 1353–9.CrossRefGoogle ScholarPubMed
Frontini, M. G., Srinivasan, S. R., Elkasabany, A. and Berenson, G. S. 2001. Distribution and cardiovascular risk correlates of serum triglycerides in young adults from a biracial community: the Bogalusa Heart Study. Atherosclerosis, 155, 1, 201–9.Google Scholar
Gould, B. W. 2002. Household composition and food expenditures in China. Agribusiness, 18, 3, 387–407.CrossRefGoogle Scholar
Grundy, S. M. 1998. Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome. American Journal of Cardiology, 81, 4A, 18B–25B.Google Scholar
He, J., Gu, D., Wu, X., Reynolds, K., Duan, X., Yao, C., Wang, J., Chen, C. S., Chen, J., Wildman, R. P., Klaq, M. J. and Whelton, P. K. 2005. Major causes of death among men and women in China. New England Journal of Medicine, 353, 11, 1124–34.CrossRefGoogle ScholarPubMed
He, J. and Whelton, P. K. 1997. Epidemiology and prevention of hypertension. Medical Clinics of North America, 81, 5, 1077–97.CrossRefGoogle ScholarPubMed
Ibrahim, M. M. and Damasceno, A. 2012. Hypertension in developing countries. Lancet, 380, 9841, 611–9.CrossRefGoogle ScholarPubMed
Jeffery, R. W. and French, S. A. 1998. Epidemic obesity in the United States: are fast foods and television viewing contributing? American Journal of Public Health, 88, 2, 277–80.Google Scholar
Joshipura, K. J., Hu, F. B., Manson, J. E., Stampfer, M. J., Rimm, E. B., Speizer, F. E., Colditz, G., Ascherio, A., Spieqelman, D. and Willett, W. C. 2001. The effect of fruit and vegetable intake on risk for coronary heart disease. Annals of Internal Medicine, 134, 12, 1106–14.Google Scholar
Kearney, P. M., Whelton, M., Reynolds, K., Muntner, P., Whelton, P. K. and He, J. 2005. Global burden of hypertension: analysis of worldwide data. Lancet, 365, 9455, 217–23.Google Scholar
Laaksonen, D. E., Niskanen, L., Nyyssonen, K., Lakka, T. A., Laukkanen, J. A. and Salonen, J. T. 2008. Dyslipidaemia as a predictor of hypertension in middle-aged men. European Heart Journal, 29, 20, 2561–8.Google Scholar
Li, Y., Li, D., Ma, C. Y., Liu, C. Y., Hui, D., Wen, Z. M. and Peng, L. P. 2012. Consumption of, and factors influencing consumption of, fruit and vegetables among elderly Chinese people. Nutrition, 28, 5, 504–8.Google Scholar
Liu, L. 2007. Cardiovascular diseases in China. Biochemistry and Cell Biology, 85, 2, 157–63.Google Scholar
Ma, H., Rae, A., Huang, J. and Rozelle, S. 2004. Chinese animal product consumption in the 1990s. Australian Journal of Agricultural and Resource Economics, 48, 4, 569–90.Google Scholar
Mendez, M. and Popkin, B. 2004. Globalization, urbanization and nutritional change in the developing world. Electronic Journal of Agricultural and Development Economics, 1, 2, 220–41.Google Scholar
Ministry of Public Health 2004. Chinese Public Health Statistics Year Book 2004. Peking Union Medical College Press, Beijing.Google Scholar
National Center for Cardiovascular Disease, Drafting Committee of Chinese Guideline for Hypertension Management 2005. Guideline for hypertension management. Chinese Journal of Hypertension, 13, supplement, 3–41.Google Scholar
Niskanen, L., Laaksonen, D. E., Nyyssönen, K., Punnonen, K., Valkonen, V. P., Fuentes, R., Tuomainen, T. P., Salonen, R., Salonen, J. T. 2004. Inflammation, abdominal obesity, and smoking as predictors of hypertension. Hypertension, 44, 6, 859–65.CrossRefGoogle ScholarPubMed
Pingali, P. 2006. Westernization of Asian diets and the transformation of food systems: implications for research and policy. Food Policy, 32, 3, 281–98.Google Scholar
Reynolds, K., Gu, D., Whelton, P. K., Wu, X., Duan, X., Mo, J., He, J. and InterASIA Collaborative Group. 2007. Prevalence and risk factors of overweight and obesity in China. Obesity, 15, 1, 10–18.Google Scholar
Smith, J. P., Strauss, J. and Zhao, Y. 2014. Healthy aging in China. Journal of the Economics of Ageing, 4, 37–43.Google Scholar
Song, A., Liang, Y., Yan, Z., Sun, B., Cai, C., Jiang, H. and Qiu, C. 2014. Highly prevalent and poorly controlled cardiovascular risk factors among Chinese elderly people living in the rural community. European Journal of Preventive Cardiology, 21, 10, 1267–74.Google Scholar
Ting, H. J., Stice, J. P., Schaff, U. Y., Hui, D. Y., Rutledge, J. C., Knowlton, A. A., Passerini, A. G. and Simon, S. I. 2007. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha. Circulation Research, 100, 3, 381–90.Google Scholar
Utsugi, M. T., Ohkubo, T., Kikuya, M., Kurimoto, A., Sato, R. I., Suzuki, K., Metoki, H., Tsubono, Y. and Imai, Y. 2008. Fruit and vegetable consumption and the risk of hypertension determined by self measurement of blood pressure at home: the Ohasama study. Hypertension Research, 31, 7, 1435–43.Google Scholar
Veeck, A. and Veeck, G. 2000. Consumer segmentation and changing food purchase patterns in Nanjing, PRC. World Development, 28, 3, 457–71.CrossRefGoogle Scholar
Watson, J. L. 1997. Introduction: transnationalism, localization, and fast foods in East Asia. In Watson, J. L. (ed.), Golden Arches East McDonald's in East Asia. Stanford University Press, Stanford, California. pp 1–10.Google Scholar
Wu, Y., Huxley, R., Li, L., Anna, V., Xie, G., Yao, C., Woodward, M., Li, X., Chalmers, J., Gao, R., Kong, L., Yang, X., China NNHS Steering Committee and China NNHS Working Group 2008. Prevalence, awareness, treatment, and control of hypertension in China: data from the China National Nutrition and Health Survey 2002. Circulation, 118, 25, 2679–86.Google Scholar
Yan, Y. 1997. McDonald's in Beijing: the localization of Americana. In Watson, J. L. (ed.), Golden Arches East McDonald's in East Asia. Stanford University Press, Stanford, California. pp. 39–45.Google Scholar
Yang, G., Wang, Y., Zeng, Y., Gao, G. F., Liang, X., Zhou, M., Wan, X., Yu, S., Jiang, Y., Naghavi, M., Vos, T., Wang, H., Lopez, A. D., Murray, C. J. 2013. Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010. Lancet, 381, 9882, 1987–2015.CrossRefGoogle Scholar
Yki-Jarvinen, H. and Taskinen, M. R. 1988. Interrelationships among insulin's antilipolytic and glucoregulatory effects and plasma triglycerides in nondiabetic and diabetic patients with endogenous hypertriglyceridemia. Diabetes, 37, 9, 1271–8.Google Scholar