A significant but largely overlooked phenomenon in twentieth-century Latin America has been the extended dominance of a single region over an entire nation. To one degree or another this type of regionalism has existed in several countries, including revolutionary Mexico, with the rise of the North and the Sonora Dynasty, and Brazil, with the control of national politics by the São Paulo-Minas Gerais axis from the 1890’s to 1930, followed by the rise of Rio Grande do Sul. In the following pages I will examine this type of regionalism as it occurred in Venezuela, in the form of Táchiran dominance over the government and armed forces for the first forty-five years of this century. My purpose is to explain how the men of one small agricultural state could maintain such long-term mastery over the country, what sort of reaction this “hegemony” produced, what the limits of regional control were, and, finally, when Táchiran rule definitively ended.