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Genetics and Sterility*

Published online by Cambridge University Press:  01 August 2014

L. Gedda
L. Gedda*
Affiliation:
Istituto di Genetica Medica e Gemellologia “G. Mendel”, Roma
*
Piazza Galeno 5, 00161 Roma, Italia

Summary

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The genetic study of sterility, although rather complex, may be carried out, as far as the parents are concerned, on the basis of existing detection methods. A number of forms of individual sterility may be detected on the basis of the caryotype (ovarian and testicular dysgenesis, hermaphroditism), while a chromosomal pathologic phenotype is missing for others, and the corresponding genotypes must be detected through clinico-genealogical methods (pseudohermaphroditism, adrenogenital syndrome, Laurence-Moon-Bardet-Biedl syndrome, hereditary malformations). It is noted that the problem of immunitary incompatibility is not sufficiently clear. Examples are presented of others forms of sterility depending on a lethal load of the conceptus, for which consanguineous marriages may be held largely responsible. Cases of sterility may also be found in relation to mental diseases. The importance of eugenic counseling is stressed.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 17 , Issue 4 , October 1968 , pp. 543 - 576
Copyright
Copyright © The International Society for Twin Studies 1968

Footnotes

*

Relazione tenuta al “Primer Congreso Argentino de Esterilidad” - Rosario, 30 Ottobre 1968.

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