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Maternal Age and Parity as Predictors of Human Twinning

Published online by Cambridge University Press:  01 August 2014

B. Bønnelykke
B. Bønnelykke*
Affiliation:
The Cytogenetic Laboratory, Aarhus Psychiatric Hospital, Risskov, Denmark
*
Department of Obstetrics and Gynecology, Vest-Agder Sentralsykehus, N-4633 Kristiansand, Norway

Abstract

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A case-control study was conducted to evaluate the association between maternal age and parity and dizygotic (DZ) and monozygotic (MZ) twinning, respectively. Mothers of all twins born alive in Denmark in 1984 or 1985 were included into the study as cases, and a random sample of mothers of singletons were controls. Data on maternal age at delivery and number of previous births were collected from the Danish Medical Birth Register. By means of logistic regression analysis, a significant and positive association was found betwen maternal age and DZ twinning, and a significant and negative association between parity and MZ twinning. No association was found for parity and DZ twinning, nor for maternal age and MZ twinning. The study suggests that human MZ twinning has predictors too, as has DZ twinning. The finding has implications for zygosity classification in future twin research.

Keywords

Maternal ageParityTwinning
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 39 , Issue 3 , July 1990 , pp. 329 - 334
Copyright
Copyright © The International Society for Twin Studies 1990

References

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