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Effect of dietary iodine on thyroid hormones and energy blood metabolites in lactating goats

Published online by Cambridge University Press:  24 May 2012

A. Nudda ,
G. Battacone ,
G. Bomboi ,
B. Floris ,
M. Decandia  and
G. Pulina
A. Nudda*
Affiliation:
Dipartimento di Agraria, Università di Sassari, via De Nicola 9, 07100 Sassari, Italy
G. Battacone
Affiliation:
Dipartimento di Agraria, Università di Sassari, via De Nicola 9, 07100 Sassari, Italy
G. Bomboi
Affiliation:
Dipartimento di Biologia Animale, Università di Sassari, via Vienna, 07100 Sassari, Italy
B. Floris
Affiliation:
Dipartimento di Biologia Animale, Università di Sassari, via Vienna, 07100 Sassari, Italy
M. Decandia
Affiliation:
Agricultural Research Agency of Sardinia – AGRIS Sardegna, Loc. Bonassai, 07100 Sassari, Italy
G. Pulina
Affiliation:
Dipartimento di Agraria, Università di Sassari, via De Nicola 9, 07100 Sassari, Italy
*
†E-mail: anudda@uniss.it
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Abstract

Aim of this work was to evaluate if long-term dietary supplementation of potassium iodide (KI) to dairy goats can influence metabolic and hormonal parameters. Thirty Sarda crossbred dairy goats were divided into three groups, which were orally administered 0 (control group; CON), 0.45 (low iodine group; LI) or 0.90 (high iodine group; HI) mg of KI/day, respectively. The daily dose of KI (76.5% of iodine) was administered as salt dissolved in water for 8 weeks. Plasma contents of nonesterified fatty acids (NEFA), urea, glucose, insulin, free triiodothyronine (FT3) and thyroxine (FT4) were determined weekly. Iodine supplementation increased significantly the FT3 hormone (P = 0.007) and FT3/FT4 ratio (P = 0.001) and tended to influence the FT4 hormone (P = 0.059). An iodine level × week of sampling interaction for NEFA (P = 0.013) evidenced a temporary concentration increase in supplemented groups. The ‘Revised Quantitative Insulin Sensitivity Check Index’ increased with KI supplementation (P ⩽ 0.01). Blood urea nitrogen (BUN) and insulin were lowered (P ⩽ 0.01) by iodine supplementation (groups LI and HI; P ⩽ 0.01). The glucose concentration evidenced an iodine level × week of sampling interaction (P = 0.025) due to an unexpected and temporary increase of its concentration in the CON group. Glucose concentration was decreased by KI supplementation only in LI group (P < 0.05). In conclusion, the daily supplementation of low doses of KI can improve insulin sensitivity and decrease BUN in dairy goats.

Keywords

iodinelactating goatsthyroid hormonesenergy blood metabolitesinsulin
Type
Nutrition
Information
animal , Volume 7 , Issue 1 , January 2013 , pp. 60 - 65
Copyright
Copyright © The Animal Consortium 2012

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