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Effect or ractopamine on growth and body composition of pigs during compensatory growth*

Published online by Cambridge University Press:  01 January 2009

A. D. Mitchell
A. D. Mitchell*
Affiliation:
USDA, Agricultural Research Service, Beltsville, MD 20705, USA
*
E-mail: Alva.Mitchell@ars.usda.gov
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Abstract

The purpose of this study was to measure the growth and body composition of pigs during normal or compensatory growth from 60 to 100 kg, without (cont) or with ractopamine (rac) supplementation (20 mg/kg of diet). Thirty-four pigs were scanned by dual X-ray absorptiometry (DXA) for body composition analysis at a starting weight of 61.4 ± 0.3 kg and at a final weight of 100.4 ± 0.5 kg. Half the pigs were fed ad libitum throughout (8 cont and 9 rac). The other half were fed at maintenance for 8 weeks and then scanned again by DXA. Following the maintenance feeding, the pigs were fed ad libitum (9 cont and 8 rac) to the final weight. Compensatory growth resulted in a 30% increase in the rate of weight gain (1.23 v. 0.94 kg/day, P < 0.05), including a 44% increase in the rate of lean tissue deposition (0.90 v. 0.62 kg/day, P < 0.05), but no change in the rate of fat deposition (0.31 v. 0.30 kg/day, P > 0.05). Feeding rac resulted in a 13% increase in the rate of weight gain (1.15 v. 1.02 kg/day, P < 0.05), consisting of a 29% increase in the rate of lean tissue deposition (0.86 v. 0.67 kg/day, P < 0.05) and an 18% reduction in the rate of fat deposition (0.27 v. 0.33 kg/day, P < 0.05). The effects of ractopamine on the rates of fat and lean tissue deposition were similar for pigs continuously fed ad libitum and those experiencing compensatory growth. Both compensatory growth and the addition of ractopamine to the diet resulted in an improvement in efficiency of protein deposition; however, ractopamine also resulted in a reduction in the efficiency of energy deposition. For both growth rate and lean tissue deposition, there was an additive effect for ractopamine and compensatory growth. Thus, feeding ractopamine will enhance the growth and body composition during compensatory growth in swine.

Keywords

swinecompensatory growthractopaminedual X-ray absorptiometry
Type
Full Paper
Information
animal , Volume 3 , Issue 1 , January 2009 , pp. 173 - 180
Copyright
Copyright © The Animal Consortium 2008

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Footnotes

*

Mention of a trade name does not constitute a guarantee or warranty by the USDA and does not imply its approval to the exclusion of other products that may be suitable.

References

Adeola, O, Darko, EA, He, P, Young, LG 1990. Manipulation of porcine carcass composition by ractopamine. Journal of Animal Science 68, 3633–3641.CrossRefGoogle ScholarPubMed
Adeola, O, Ball, RO, Young, LG 1992. Porcine skeletal muscle myofibrillar protein synthesis is stimulated by ractopamine. Journal of Nutrition 122, 488–495.CrossRefGoogle ScholarPubMed
Anderson, DB, Paxton, RE, Mowrey, DH 1989. The effect of dietary protein on the additivity of ractopamine and porcine somatotropin on nitrogen metabolism of finishing pigs. Journal of Animal Science 67 (Suppl. 1), 221.Google Scholar
Bark, LJ, Stahly, TS, Cromwell, GL, Miyat, J 1992. Influence of genetic capacity for lean tissue growth on rate and efficiency of tissue accretion in pigs fed ractopamine. Journal of Animal Science 70, 3391–3400.CrossRefGoogle ScholarPubMed
Bergen, WG, Johnson, SE, Skjaerlund, DM, Babiker, AS, Ames, NK, Merkel, RA, Anderson, DB 1989. Muscle protein metabolism in finishing pigs fed ractopamine. Journal of Animal Science 67, 2255–2262.CrossRefGoogle ScholarPubMed
Carr, SN, Ivers, DJ, Anderson, DB, Jones, DJ, Mowrey, DH, England, MB, Killefer, J, Rincker, PJ, McKeith, FK 2005. The effects of ractopamine hydrochloride on lean carcass yields and pork quality characteristics. Journal of Animal Science 83, 2886–2893.CrossRefGoogle ScholarPubMed
Crome, PK, McKeith, FK, Carr, TR, Jones, DJ, Mowrey, DH, Cannon, JE 1996. Effect of ractopamine on growth performance, carcass composition, and cutting yields of pigs slaughtered at 107 and 125 kilograms. Journal of Animal Science 74, 709–716.CrossRefGoogle ScholarPubMed
Dunshea, FR, King, RH, Campbell, RG, Sainz, RD, Kim, YS 1993. Interrelationships between sex and ractopamine on protein and lipid deposition in rapidly growing pigs. Journal of Animal Science 71, 2919–2930.CrossRefGoogle ScholarPubMed
Dunshea, FR, Eason, PJ, Campbell, RG, King, RH 1998. Interrelationships between dietary ractopamine, energy intake, and sex in pigs. Australian Journal of Agricultural Research 49, 565–574.CrossRefGoogle Scholar
Fernández, JA, Oksbjerg, N, Jørgensen, H 1998. Effect of salbutamol on body composition and energy utilization in growing pigs fed two levels of protein. In Energy metabolism farm animals (ed. K McCracken, FF Unsworth and ARG Wylie), pp. 249–252. CAB International, Wallingford, UK.Google Scholar
Gädeken, D, Bohme, H, Oslage, HJ 1983. Protein and energy metabolism in growing pigs as influenced by compensatory growth. Archiv furTierernährung 33, 125–140.CrossRefGoogle Scholar
Gunawan, AM, Richert, BT, Schinckel, AP, Grant, AL, Gerrard, DE 2007. Ractopamine induces differential gene expression in porcine skeletal muscles. Journal of Animal Science 85, 2115–2124.CrossRefGoogle ScholarPubMed
Hansen, JA, Yen, JT, Nelssen, JL, Nienaber, JA, Goodband, RD, Wheeler, TL 1997. Effects of somatotropin and salbutamol in three genotypes of finishing barrows: growth, carcass and calorimeter criteria. Journal of Animal Science 75, 1798–1809.CrossRefGoogle ScholarPubMed
He, P, Aherne, FX, Thompson, JR, Schaefer, AL, Merrill, JK 1993. Effect of ractopamine on carcass characteristics and joint cartilage soundness in finishing pigs. Canadian Journal of Animal Science 73, 169–176.CrossRefGoogle Scholar
Heyer, A, Lebret, B 2007. Compensatory growth response in pigs: effects on growth performance, composition of weight gain at carcass and muscle levels, and meat quality. Journal of Animal Science 85, 769–778.CrossRefGoogle ScholarPubMed
Hornick, JL, Van Eenaeme, C, Gérard, O, Dufrasne, I, Istasse, L 2000. Mechanisms of reduced and compensatory growth. Domestic Animal Endocrinology 19, 121–132.CrossRefGoogle ScholarPubMed
Jones, RW, Easter, RA, McKeith, FK, Dalrymple, RH, Maddock, HM, Bechtel, PJ 1985. Effect of the beta-adrenergic agonist cimaterol (CL 263, 780) on the growth and carcass characteristics of finishing swine. Journal of Animal Science 61, 905–913.CrossRefGoogle ScholarPubMed
Jones, DJ, Anderson, DB, Waitt, WP, Waganer, JF, Mowery, DH 1989. Effect of ractopamine hydrochloride (RAC) and pituitary derived porcine somatotropin (pPST) alone and in combination on swine growth and carcass parameters. Journal of Animal Science 67 (Suppl. 1), 221.Google Scholar
Kolstad, K, Vangen, O 1996. Breed differences in maintenance requirements of growing pigs when accounting for changes in body composition. Livestock Production Science 47, 23–32.CrossRefGoogle Scholar
Lovatto, PA, Sauvant, D, Noblet, J, Dubois, S, van Milgen, J 2006. Effects of feed restriction and subsequent refeeding on energy utilization in growing pigs. Journal of Animal Science 84, 3329–3336.CrossRefGoogle ScholarPubMed
McMeekan, CP 1940. Growth and development in the pig, with special reference to carcass quality characters. Part I. Journal of Agricultural Science 30, 276–343.CrossRefGoogle Scholar
Mersmann, HJ, MacNeil, MD, Seideman, SC, Pond, WG 1987. Compensatory growth in finishing pigs after feed restriction. Journal of Animal Science 64, 752–764.CrossRefGoogle Scholar
Mills, SE, Spurlock, ME, Smith, DJ 2003. β-Adrenergic receptor subtypes that mediate ractopamine stimulation of lipolysis. Journal of Animal Science 81, 662–668.CrossRefGoogle ScholarPubMed
Mimbs, KJ, Pringle, TD, Azain, MJ, Meers, SA, Armstrong, TA 2005. Effects of ractopamine on performance and composition of pigs phenotypically sorted into fat and lean groups. Journal of Animal Science 83, 1361–1369.CrossRefGoogle ScholarPubMed
Mitchell, AD, Pursel, VG 2003. Efficiency of energy deposition and body composition of control and IGF-I transgenic pigs. In Progress in research on energy and protein metabolism. EAAP scientific series (ed. WB Souffrant and CC Metges), vol. 109, pp. 61–64. Wageningen Academic Publishers, Wageningen, The Netherlands.CrossRefGoogle Scholar
Mitchell, AD, Solomon, MB, Steele, NC 1990. Response of low and high protein select lines of pigs to the feeding of the beta-adrenergic agonist ractopamine (phenethanolamine). Journal of Animal Science 68, 3226–3232.CrossRefGoogle Scholar
Mitchell, AD, Conway, JM, Scholz, AM 1996. Incremental changes in total and regional body composition of growing pigs measured by dual-energy X-ray absorptiometry. Growth, Development and Aging 60, 95–105.Google ScholarPubMed
Mitchell, AD, Scholz, AM, Pursel, VG, Evock-Clover, CM 1998. Composition analysis of pork carcasses by dual-energy X-ray absorptiometry. Journal of Animal Science 76, 2104–2114.CrossRefGoogle ScholarPubMed
Mitchell, AD, Scholz, AM, Pursel, VG 2003. Changes in body composition when young pigs are restricted to near maintenance dietary intake. International Journal of Body Composition Research 1, 123–128.Google Scholar
Moody, DE, Hancock, DL, Anderson, DB 2000. Phenethanolamine repartitioning agents. In Farm animal metabolism and nutrition (ed. JPF D’Mello), pp. 65–96. CAB International, Wallingford, UK.CrossRefGoogle Scholar
Number Cruncher Statistical System (NCSS) 2000. Statistical software. Kaysville, Utah, USA.Google Scholar
Peterla, TA, Scanes, CG 1990. Effect of β-adrenergic agonists on lipolysis and lipogenesis by porcine adipose tissue in vitro. Journal of Animal Science 68, 1024–1029.CrossRefGoogle ScholarPubMed
Spurlock, ME, Cusumano, JC, Mills, SE 1993. The affinity of ractopamine, clenbuterol, and L-644,969 for the β-adrenergic receptor population in porcine adipose tissue and skeletal muscle membrane. Journal of Animal Science 71, 2061–2065.CrossRefGoogle ScholarPubMed
Stamataris, C, Kyriazakis, I, Emmans, GC 1991. The performance and body composition of young pigs following a period of growth retardation by food restriction. Animal Production 53, 373–381.Google Scholar
Statgraphics Plus 2000. Manugistics, Inc., Rockville, MD, USA.Google Scholar
Stites, CR, McKeith, FK, Singh, SD, Bechtel, PJ, Mowrey, DH, Jones, DJ 1991. The effect of ractopamine hydrochloride on the carcass cutting yields of finishing swine. Journal of Animal Science 69, 3094–3101.CrossRefGoogle ScholarPubMed
Therkildsen, M, Riis, B, Karlsson, A, Kristensen, L, Ertbjeerg, P, Rurslow, PP, Dall Aaslyng, M, Oksbjerg, N 2002. Compensatory growth response in pigs, muscle protein turn-over and meat texture: effects of restriction/realimentation period. Animal Science 75, 367–377.CrossRefGoogle Scholar
Watkins, LE, Jones, DJ, Mowrey, DH, Anderson, DB, Veenhuizen, EL 1990. The effect of various levels of ractopamine hydrochloride on the performance and carcass characteristics of finishing swine. Journal of Animal Science 68, 3588–3595.CrossRefGoogle ScholarPubMed
Wilson, PN, Osbourn, DF 1960. Compensatory growth after underenutrition in mammals and birds. Biological Reviews of the Cambridge Philosophical Society 35, 324–363.CrossRefGoogle ScholarPubMed
Yen, JT, Nienaber, JA, Klindt, J, Crouse, JD 1991. Effect of ractopamine on growth, carcass traits, and fasting heat production of US contemporary crossbred and Chinese Meishan pure- and crossbred pigs. Journal of Animal Science 69, 4810–4822.CrossRefGoogle ScholarPubMed