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Mammary gland secretion: hormonal coordination of endocytosis and exocytosis

Published online by Cambridge University Press:  17 August 2009

S. Truchet  and
M. Ollivier-Bousquet
S. Truchet
Affiliation:
INRA, UR1196 Génomique et Physiologie de la Lactation, F78352 Jouy-en-Josas, France
M. Ollivier-Bousquet*
Affiliation:
INRA, UR1196 Génomique et Physiologie de la Lactation, F78352 Jouy-en-Josas, France
*
†E-mail: michele.ollivier@jouy.inra.fr
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Abstract

The mammary epithelium coordinates the uptake of milk precursors and the transport of milk components in order to produce milk of relatively constant composition at a particular stage of lactation, as long as the mammary gland is healthy. The mammary epithelial cell controls the uptake of blood-borne molecules at its basal side and the release of products into milk at its apical side, through mechanisms of internalization (endocytosis) and mechanisms of release (exocytosis). These events are strictly dependent on the physiological stage of the mammary gland. This review addresses the mechanisms responsible for these processes and points out new questions that remain to be answered concerning possible interconnections between them, for an optimal milk secretion.

Keywords

mammary epithelial cellmilk secretionhormonal regulation
Type
Full Paper
Information
animal , Volume 3 , Issue 12 , December 2009 , pp. 1733 - 1742
Copyright
Copyright © The Animal Consortium 2009

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