Hostname: page-component-cd9895bd7-fscjk Total loading time: 0 Render date: 2024-12-30T20:53:37.013Z Has data issue: false hasContentIssue false
  • English
  • Français

Cue fascination: A new vulnerability in drug addiction

Published online by Cambridge University Press:  29 July 2008

John Sarnecki ,
Rebecca Traynor  and
Michael Clune
John Sarnecki
Affiliation:
Department of Philosophy, University of Toledo, Toledo, OH, 43606-3390
Rebecca Traynor
Affiliation:
Department of Philosophy, University of Toledo, Toledo, OH, 43606-3390
Michael Clune
Affiliation:
Department of English, University of South Florida, Tampa, FL 33620-5550. john.sarnecki@utoledo.eduhttp://homepages.utoledo.edu/jsarnec/index.htmrebecca.traynor@utoledo.edumclune@cas.usf.eduhttp://english.usf.edu/faculty/mclune/
Get access Rights & Permissions [Opens in a new window]

Abstract

Redish et al. propose a constellation of vulnerabilities inherent in the brain's decision-making system. They allow over-attention to cues a minor role in drug addiction. We think this is inadequate. Using the established links among drug cues, dopamine, and novelty, we propose a fuller account of this key feature of addiction, which we call the phenomenon of cue fascination.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 31 , Issue 4 , August 2008 , pp. 458 - 459
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Berridge, K. C. & Robinson, T. E. (2003) Parsing reward. Trends in Neurosciences 26(9):507–13.CrossRefGoogle ScholarPubMed
Carter, B. L. & Tiffany, S. T. (1999) Meta-analysis of cue-reactivity in addiction research. Addiction 94(3):327–40.CrossRefGoogle ScholarPubMed
Freeman, A. S., Meltzer, L. T. & Bunney, B. S. (1985) Firing properties of substantia nigra dopaminergic neurons in freely moving rats. Life Sciences 36(20):1983–94.CrossRefGoogle ScholarPubMed
Garris, P. A., Kilpatrick, M., Bunin, M. A., Michael, D., Walker, Q. D. & Wightman, R. M. (1999) Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation. Nature 398:67–69.CrossRefGoogle ScholarPubMed
Kapur, S., Mizrahi, R. & Li, M. (2005) From dopamine to salience to psychosis – linking biology, pharmacology and phenomenology of psychosis. Schizophrenic Research 79(1):59–68.CrossRefGoogle ScholarPubMed
Kotler, M., Cohen, H., Segman, R., Gritsenko, I., Nemanov, L., Lerer, B., Kramer, I., Zer-Zion, M., Kletz, I. & Ebstein, R. P. (1997) Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects. Molecular Psychiatry 2:251–54.CrossRefGoogle ScholarPubMed
Robinson, T. E. & Berridge, K. C. (1993) The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Research Reviews 18(3):247–336.CrossRefGoogle ScholarPubMed
Robinson, T. E. & Berridge, K. C. (2004) Incentive-sensitization and drug “wanting” (Reply). Psychopharmacology 171:352–53.CrossRefGoogle Scholar
Rosse, R. B., Fay-McCarthy, M., Collins, J. P., Risher-Flowers, D., Alim, T. N. & Deutsch, S. I. (1993) Transient compulsive foraging behavior associated with crack cocaine use. American Journal of Psychiatry 150:155–56.Google ScholarPubMed
Schultz, W. (1998) Predictive reward signal of dopamine neurons. Journal of Neurophysiology 80:1–27.CrossRefGoogle ScholarPubMed
Zinberg, N. E. (1984) Drug, set, and setting: The basis for controlled intoxicant use. Yale University Press.Google Scholar