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Absorption of lysine and methionine from the proximal colon of the piglet

Published online by Cambridge University Press:  09 March 2007

Alison J. Darragh ,
Peter D. Cranwell  and
Paul J. Moughan
Alison J. Darragh
Affiliation:
Department of Animal Science, Massey University, Palmerston North, New Zealand
Peter D. Cranwell
Affiliation:
School of Agriculture, La Trobe University, Bundoora, Victoria 3083, Australia
Paul J. Moughan
Affiliation:
Department of Animal Science, Massey University, Palmerston North, New Zealand
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Abstract

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The present study aimed to determine whether lysine and/or methionine are absorbed in nutritionally significant amounts from the proximal colon of milk-formula-fed piglets (15–32 d old; 2.0–7.4 kg liveweight). Piglets, surgically prepared with simple catheters which allowed infusion into the proximal colon, were randomly allocated to one of two milk-formula diets which were either 40 % deficient in lysine (L– diet) or 60% deficient in methionine and 40% deficient in cysteine (S – diet), yet balanced for all other amino acids. The piglets were individually bottle-fed the milk-formula diets seven times daily at 2 h intervals between 08.00 and 20.00 hours. Physiological saline (9 g NaCl/l) or an isotonic solution containing the deficient amino acid was infused via the catheter at each feeding. The experimental procedure followed a cross-over design. Total daily excretions of urinary urea and total N were determined. There were no significant differences (P > 0.05) in urinary N metabolite excretion for piglets infused with amino acids compared with those infused with saline. Lysine and methionine do not appear to be absorbed in nutritionally significant amounts from the proximal colon of the milk-fed piglet.

Keywords

PigletAmino acidsAbsorptionProximal colon
Type
absorption of lysine and methiionine from the colon
Information
British Journal of Nutrition , Volume 71 , Issue 5 , May 1994 , pp. 739 - 752
Copyright
Copyright © The Nutrition Society 1994

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