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Early life undernutrition in rats

2. Some contractile properties of skeletal muscles from adult animals

Published online by Cambridge University Press:  04 June 2009

A. C. Wareham
Affiliation:
Department of Physiology, University of Manchester, Manchester M13 9PT
M. Mahon
Affiliation:
Department of Anatomy, University of Manchester, Manchester M13 9PT
K.S Bedi
Affiliation:
Department of Child Health, University of Manchester, Manchester M13 9PT
J. L. Smart
Affiliation:
Department of Child Health, University of Manchester, Manchester M13 9PT
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Abstract

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1. The contractile properties of soleus and extensor digitorum longus muscles from animals at 12 months of age whose mothers had been undernourished during pregnancy and lactation (PU rats) have been compared with those of muscles from age-matched controls.

2. Body-weight and muscle wet weight of PU rats was significantly reduced. Muscle: body-weight values were, however, no different from controls.

3. No significant alterations in whole muscle speeds of contraction or relaxation could be delected when compared with those of age-matched controls.

4. Twitch and tetanic forces of both SOL and EDL were greater per unit weight of muscle in PU rats. Apart from SOL twitch these differences were significant. The tetanus:twitch values were, however, not different.

Type
Papers of direct reference to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1982

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