Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-24T23:26:17.309Z Has data issue: false hasContentIssue false
  • English
  • Français

Toxicological and genetical studies of organophosphorus-resistance in Cimex lectularius L

Published online by Cambridge University Press:  10 July 2009

M. Feroz
M. Feroz
Affiliation:
London School of Hygiene & Tropical Medicine, Keppel St., London, W.C.1
Get access Rights & Permissions [Opens in a new window]

Extract

A range of insecticides were tested on a resistant strain of bed-bugs (Cimex lectularius L.) from Israel. Resistance was restricted to organophosphorus compounds. Only some of the phosphorothioate compounds were involved, but there was no simple indication of the resistance mechanism on basis of structure of the compounds.

Nine malathion analogues were tested on the bed-bugs, and relative levels of resistance to them compared with insect strains specifically resistant to malathion. Distinct differences in the bed-bug spectrum suggested that a carboxyesterase was not solely responsible for resistance. This was further supported by the ineffectiveness of triphenylphosphate against malathion-resistance in the bugs.

The F1 progeny from reciprocal mass crosses were tested with malathion. Their response, in both cases, resembled the susceptible type, indicating a recessive autosomal character, a result unique in organophosphorus-resistance. Tests on F2 and backcrosses indicated that a single gene was responsible. Results using fenchlorphos were quite similar and probably the same gene (and mechanism) is involved.

Type
Original Articles
Information
Bulletin of Entomological Research , Volume 59 , Issue 3 , December 1969 , pp. 377 - 382
Copyright
Copyright © Cambridge University Press 1969

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barkai, A. (1964). A preliminary survey of bed-bug resistance to organophosphorus compounds in Israel.—WHO/Vector Control/58, pp. 1–5.Google Scholar
Bell, J. D. & Busvine, J. R. (1967). Synergism of organophosphates in Musca domestica and Chrysomya putoria.—Entomologia exp. appl. 10, 263–269.CrossRefGoogle Scholar
Brown, A. W. A. (1967). Genetics of insecticide resistance in insect vectors of disease. In Wright, J. W. & Pal, R. Ed. Amsterdam, Elsevier.—Genetics of insect vectors of disease, 505–552.Google Scholar
Busvine, J. R. (1958). Insecticide-resistance in bed-bugs.—Bull. Wld Hlth Org. 19, 1041–1052.Google ScholarPubMed
Dauterman, W. C. & Matsumura, F. (1962). Effect of malathion analogs upon resistant and susceptible Culex tarsalis mosquitoes.—Science, N.Y. 138 no. 3541, 694–695.CrossRefGoogle Scholar
Dittrich, V. (1961). Populationsgenetische Unterschungen an normalen und phosphorsäure-ester-resistenten Stämmen von Tetranychus urticae Koch.—Z. angew. Ent. 48, 34–57.CrossRefGoogle Scholar
Dittrich, V. (1963 a). A recessive factor of organophosphate-resistance in populations of the two-spotted mite, Tetranychus telarius.—J. econ. Ent. 56, 182–184.CrossRefGoogle Scholar
Dittrich, V. (1963 b). Investigations on OP-resistance of two genetically differing populations of Tetranychus urticae K.—Entomologia exp. appl. 6, 10–20.CrossRefGoogle Scholar
Dyte, C. E. & Rowlands, D. G. (1968). The metabolism and synergism of malathion in resistant and susceptible strains of Tribolium castaneum (Herbst) (Coleoptera, Tenebrionidae).—J. stored prod. Res. 4, 157–173.CrossRefGoogle Scholar
Helle, W. (1962). Genetics of resistance to organophosphorus compounds and its relation to diapause in Tetranychus urticae Koch (Acari).—Tijdschr. Plziekt. 68, 155–195. (Proefschr. Univ. Amsterdam.)Google Scholar
Helle, W. (1965). Resistance in the Acarina: Mites.—Adv. Acarology 2, 71–93.Google Scholar
Matsumura, F. & Dauterman, W. C. (1964). Effect of malathion analogues on a malathionresistant housefly strain which possesses a detoxication enzyme, carboxyesterase.—Nature, Lond. 202 no. 4939, 1356–1358.CrossRefGoogle ScholarPubMed
O'Brien, R. D. (1967). Insecticides: Action and metabolism.—332 pp. New York, &c, Academic Pr.Google Scholar
Plapp, F. W. jr & Eddy, G. W. (1961). Synergism of malathion against resistant insects.—Science, N.Y. 134 no. 3495, 2043–2044.CrossRefGoogle ScholarPubMed
Plapp, F. W. jr, Orchard, R. D. & Morgan, J. W. (1965). Analogs of parathion and malathion as substitute insecticides for the control of resistant houseflies and the mosquito Culex tarsalis.—J. econ. Ent. 58, 953–956.CrossRefGoogle ScholarPubMed
Schulten, G. G. M. (1968). Genetics of organophosphate-resistance in the two-spotted spider mite Tetranychus urticae Koch.—x + 57 pp. Ph.D. thesis. Univ. Amsterdam.Google Scholar
Townsend, M. G. & Busvine, J. R. (in press). The mechanism of malathion-resistance in the blowfly Chrysomya putoria.—Entomologia exp. appl.Google Scholar
Tsukamoto, M. (1963). The log dosage-probit mortality curve in genetic researches of insect resistance to insecticides.—Botyu-Kagaku 28, 91–98.Google Scholar