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The Concurrence of Multiple Sclerosis and Amyotrophic Lateral Sclerosis

Published online by Cambridge University Press:  18 September 2015

Walter J. Hader ,
Bohdan Rozdilsky  and
Cheranada P. Nair
Walter J. Hader*
Affiliation:
Departments of Rehabilitation Medicine, Pathology (Neuropathology), University Hospital, Saskatoon, Saskatchewan and the Plains Health Centre, Regina, Saskatchewan
Bohdan Rozdilsky
Affiliation:
Departments of Rehabilitation Medicine, Pathology (Neuropathology), University Hospital, Saskatoon, Saskatchewan and the Plains Health Centre, Regina, Saskatchewan
Cheranada P. Nair
Affiliation:
Departments of Rehabilitation Medicine, Pathology (Neuropathology), University Hospital, Saskatoon, Saskatchewan and the Plains Health Centre, Regina, Saskatchewan
*
Department of Rehabilitation Medicine, University Hospital, Saskatoon, Saskatchewan, Canada S7N 0X0
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Abstract:

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We report the clinical and pathological findings of the unusual combination of two idiopathic central nervous system diseases, multiple sclerosis and amyotrophic lateral sclerosis in a 56 year old physician with a twenty-seven year history of a disease initially characterized by relapses and remissions, followed by an eight year quiescent period. During the last year of life there was rapid deterioration with development of generalized weakness, atrophy, weight loss and fasciculations of body and tongue, and associated difficulty with swallowing and sudden respiratory failure. The autopsy confirmed characteristic “burned out” plaques of multiple sclerosis and anterior horn cell and axonal degeneration of amyotrophic lateral sclerosis.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 13 , Issue 1 , February 1986 , pp. 66 - 69
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

References

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