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Early and Late Complications Following Dynamic Stereotactic Radiosurgery and Fractionated Stereotactic Radiotherapy

Published online by Cambridge University Press:  18 September 2015

R. McKenzie Michal ,
Sohami Luis ,
Caron Jean-Louis ,
Oliver Andre ,
Villemure Jean-Guy  and
B. Podgorsak Ervin
R. McKenzie Michal*
Affiliation:
Department of Oncology (Division of Radiation Oncology) (M.R.M., L.S., E.B.P.), and the Department of Neurosurgery (J-L.C. A.O., J-G.V.). McGill University, Montreal
Sohami Luis*
Affiliation:
Department of Oncology (Division of Radiation Oncology) (M.R.M., L.S., E.B.P.), and the Department of Neurosurgery (J-L.C. A.O., J-G.V.). McGill University, Montreal
Caron Jean-Louis*
Affiliation:
Department of Oncology (Division of Radiation Oncology) (M.R.M., L.S., E.B.P.), and the Department of Neurosurgery (J-L.C. A.O., J-G.V.). McGill University, Montreal
Oliver Andre*
Affiliation:
Department of Oncology (Division of Radiation Oncology) (M.R.M., L.S., E.B.P.), and the Department of Neurosurgery (J-L.C. A.O., J-G.V.). McGill University, Montreal
Villemure Jean-Guy*
Affiliation:
Department of Oncology (Division of Radiation Oncology) (M.R.M., L.S., E.B.P.), and the Department of Neurosurgery (J-L.C. A.O., J-G.V.). McGill University, Montreal
B. Podgorsak Ervin*
Affiliation:
Department of Oncology (Division of Radiation Oncology) (M.R.M., L.S., E.B.P.), and the Department of Neurosurgery (J-L.C. A.O., J-G.V.). McGill University, Montreal
*
Department of Radiation Oncology, Montreal General Hospital, 1650 Cedar Avenue, Montreal, Qudbec, Canada H3G 1A4
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Abstract:

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Between December 1986 and June 1990, 112 patients (116 lesions), underwent treatment with dynamic stereotactic radiosurgery at McGill University. Of the treated lesions, 59 were arteriovenous malformations and 53 were a variety of other neoplastic or non-neoplastic conditions. In 86 lesions, the treatment was delivered in a single fraction and the treatment of the remaining 30 lesions was fractionated. Complications attributed to treatment developed in seven of the 112 patients (6.3%). No relationship was found between complications and prescribed dose, fractionation, collimator diameter, type and anatomical region of the lesion that was treated, or previous irradiation. Although extensive clinical experience will be necessary to determine optimal total doses, the potential role of fractionated treatment, and the tolerance of critical structures to radiosurgery, the relatively low incidence of complications in our series allows us to conclude that radiosurgery is well tolerated by the vast majority of patients.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 20 , Issue 4 , November 1993 , pp. 279 - 285
Copyright
Copyright © Canadian Neurological Sciences Federation 1993

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