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Intracranial Endodermal Sinus Tumour — Role for Chemotherapy

Published online by Cambridge University Press:  18 September 2015

Brian A. Anderson*
Affiliation:
Section of Neurology, Department of Medicine, University of Manitoba, Winnipeg
*
St. Boniface General Hospital, 409 Tache Avenue, Winnipeg, Manitoba, Canada R2H 2A6
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Abstract:

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Pineal tumours are commonly of germ cell origin. The endodermal sinus tumour is a rare histologic subtype that is highly malignant and radioresistant. A single case is described and compared to six reported intracranial cases in which chemotherapy was used in addition to surgery and/or radiation. Although a beneficial effect of chemotherapy cannot be proven, the probable benefit in non-CNS cases requires that it be strongly considered. A uniform approach to diagnosis, investigation and treatment for intracranial tumours of this type is suggested.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

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