Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-07T21:20:27.706Z Has data issue: false hasContentIssue false
  • English
  • Français

Intracranial Endodermal Sinus Tumour — Role for Chemotherapy

Published online by Cambridge University Press:  18 September 2015

Brian A. Anderson
Brian A. Anderson*
Affiliation:
Section of Neurology, Department of Medicine, University of Manitoba, Winnipeg
*
St. Boniface General Hospital, 409 Tache Avenue, Winnipeg, Manitoba, Canada R2H 2A6
Rights & Permissions [Opens in a new window]

Abstract:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Pineal tumours are commonly of germ cell origin. The endodermal sinus tumour is a rare histologic subtype that is highly malignant and radioresistant. A single case is described and compared to six reported intracranial cases in which chemotherapy was used in addition to surgery and/or radiation. Although a beneficial effect of chemotherapy cannot be proven, the probable benefit in non-CNS cases requires that it be strongly considered. A uniform approach to diagnosis, investigation and treatment for intracranial tumours of this type is suggested.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 14 , Issue 2 , May 1987 , pp. 166 - 171
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

References

1.Russell, DS, Rubinstein, LJ. Pineal tumours. In: Pathology of tumours of the nervous system Williams and Wilkins 1977; 283–2981.Google Scholar
2.Jennings, MT, Gelman, R, Hochberg, F. Intracranial germ-cell tumours: natural history and pathogenesis. J Neurosurg 1985; 63: 155–167.CrossRefGoogle ScholarPubMed
3.Borit, A. Embryonal carcinoma of the pineal region. J Pathol 1969; 97: 165–168.CrossRefGoogle ScholarPubMed
4.Jellinger, K. Primary intracranial germ cell tumours. Acta neuropathologica 1973; 25: 291–306.CrossRefGoogle ScholarPubMed
5.Murovic, JA, Ongley, JP, Parker, JC, et al. Manifestations and therapeutic considerations in pineal yolk-sac tumours. Case report. J Neurosurg 1981; 55: 1303–307.CrossRefGoogle ScholarPubMed
6.Takei, Y, Pearl, GS. Ultrastructural study of intracranial yolk sac tumour. Cancer 1981; 48: 2038–2046.3.0.CO;2-M>CrossRefGoogle Scholar
7.Gershenson, DM, del Junco, G, Herson, J, et al. Endodermal sinus tumour of the ovary. Obstet Gynecol 1983; 61: 194–202.Google Scholar
8.Kurman, RJ, Norris, HJ. Endodermal sinus tumour of the ovary. A clinical and pathologic analysis of 71 cases. Cancer 1976; 38: 2404–2419.3.0.CO;2-3>CrossRefGoogle ScholarPubMed
9.Prioleau, G, Wilson, CB. Endodermal sinus tumour of the pineal region. Case report. Cancer 1976; 38: 2489–2493.3.0.CO;2-J>CrossRefGoogle ScholarPubMed
10.Ungerleider, RS, Donaldson, SS, Warnke, RA, et al. Endodermal sinus tumour. The Stanford experience and the first reported case arising in the vulva. Cancer 1978; 41: 1627–1634.3.0.CO;2-K>CrossRefGoogle ScholarPubMed
11.Einhorn, LH, Donohue, J. Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer. Ann Intern Med 1977; 87: 293–298.CrossRefGoogle ScholarPubMed
12.Arita, N, Bitoh, S, Ushio, Y, et al. Primary pineal endodermal sinus tumour with elevated serum and CSF alphafetoprotein levels. Case report. J Neurosurg 1980; 53: 244–248.CrossRefGoogle ScholarPubMed
13.Wilson, ER, Takei, Y, Bikoff, WT, et al. Abdominal metastases of primary intracranial yolk sac tumours through ventriculoperitoneal shunts: report of three cases. Neurosurgery 1979; 5(3): 356–364.CrossRefGoogle ScholarPubMed
14.Eberts, TJ, Ransberg, RC. Primary intracranial endodermal sinus tumour. Case report. J Neurosurg 1979; 50: 246–252.CrossRefGoogle ScholarPubMed
15.Tavcar, D, Robboy, SJ, Chapman, P. Endodermal sinus tumour of the pineal region. Cancer 1980; 45: 2646–2651.3.0.CO;2-T>CrossRefGoogle Scholar
16.Bamberg, M, Metz, K, Alberti, W, et al. Endodermal sinus tumour of the pineal region. Cancer 1984; 54: 903–906.3.0.CO;2-D>CrossRefGoogle Scholar
17.Pecker, J, Scarabin, JM, Vallee, B. et al. Treatment in tumours of the pineal region: value of stereotaxic biopsy. Surg Neurol 1979; 12: 341–348.Google Scholar
18.Stein, BM. Tumours of the pineal region.In: Youmans, JR, ed. Neurological Surgery. WB Saunders 1982; 5: 2863–2871.Google Scholar
19.Schultz, H, Sell, A, Norgaard-Pedersen, B. et al. Serum alphafetoprotein and human chorionic gonadotropin as markers for the effect of postoperative radiation therapy and/or chemotherapy in testicular cancer . Cancer 1978; 42: 2182–2186.3.0.CO;2-7>CrossRefGoogle ScholarPubMed
20.Siegal, T, Pfeffer, R, Catane, R. et al. Successful chemotherapy of recurrent intracranial germinoma with spinal metastases. Neurology (Cleveland) 1983; 33: 631–3.CrossRefGoogle ScholarPubMed
21.Arita, N, Arita, Y, Hayakawa, T. et al. Serum levels of alphafetoprotein, human chorionic gonadotropin and carcinoembryonic antigen in patients with primary intracranial germ cell tumours. Oncodev Biol Med 1980; 1: 235–240.Google Scholar
22.Bjornsson, J, Scheithauer, BW, Okazaki, H, et al. Intracranial germ cell tumours: pathobiological and immunohistochemical aspects of 70 cases. J Neuropathol Exp Neurol 1985; 44: 32–46.CrossRefGoogle ScholarPubMed
23.Ginsberg, S, Kirshner, J, Reich, S, et al. System chemotherapy for a primary germ cell tumour of the brain: a pharmacokinetic study. Cancer Treat Rep 1981; 65: 477–483.Google Scholar
24.Logothetis, CJ, Samuels, ML, Trindade, A, et al. The prognostic significance of endodermal sinus tumour histology among patients treated for stage 111 nonseminomatous germ cell tumours of the testes. Cancer 1984; 53: 122–128.3.0.CO;2-B>CrossRefGoogle Scholar
25. Rusch, VW, Logothetis, C, Samuels, M. Endodermal sinus tumour of the mediastinum. Chest 1984; 86(5): 745–747.CrossRefGoogle Scholar
26. Neuwelt, EA, Frenkel, EP, Smith, RG. Suprasellar germinomas (ectopic pinealomas): aspects of immunological characterization and successful chemotherapeutic responses in recurrent disease. Neurosurgery 1980; 7(4): 352–358.CrossRefGoogle ScholarPubMed
27. Olsen, MM, Raffensperger, JG, Gonzalez-Crussi, F. et al. Suprasellar germinomas (ectopic pinealomas): aspects of immunological characterization and successful chemotherapeutic responses in recurrent disease. Journal of Pediatric Surgery 1982; 17(6): 832–838.CrossRefGoogle Scholar