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Molecular Interactions Modulating Neuronal Survival and Growth

Published online by Cambridge University Press:  18 September 2015

R.J. Riopelle ,
K.E. Dow ,
V.M.K. Verge  and
P.M. Richardson
R.J. Riopelle*
Affiliation:
Department of Medicine, Queen's University, Kingston
K.E. Dow
Affiliation:
Department of Pediatrics, Queen's University, Kingston
V.M.K. Verge
Affiliation:
Department of Surgery, McGill University, Montreal
P.M. Richardson
Affiliation:
Department of Surgery, McGill University, Montreal
*
Apps Medical Research Centre, Kingston General Hospital, Kingston, Ontario, Canada K7L 2V7
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Abstract:

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The extracellular environment of the neuron provides a heterogeneous milieu of survival and growth modulating molecular species subserving regulatory signals that operate in development, meditate activity-dependent enduring changes in synaptic connectivity, and promote or inhibit survival and axonal regeneration following insult. Parallel distributed processing networks in neurons, activated by these molecular species, can likely be recruited selectively to serve specific needs of the organism.

Information

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 18 , Issue S3 , August 1991 , pp. 398 - 402
Copyright
Copyright © Canadian Neurological Sciences Federation 1991

References

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