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A Preliminary Study of Dynamic Muscle Function in Hereditary Ataxia

Published online by Cambridge University Press:  18 September 2015

C. Richards ,
J.P. Bouchard ,
R. Bouchard  and
H. Barbeau
C. Richards
Affiliation:
Centre de Recherche en Neurobiologie, École de Réadaptation, Université Laval, and Département des Sciences Neurologiques, Hôpital de l'Enfant-Jésus, 1401, 18e Rue, Québec
J.P. Bouchard
Affiliation:
Centre de Recherche en Neurobiologie, École de Réadaptation, Université Laval, and Département des Sciences Neurologiques, Hôpital de l'Enfant-Jésus, 1401, 18e Rue, Québec
R. Bouchard
Affiliation:
Centre de Recherche en Neurobiologie, École de Réadaptation, Université Laval, and Département des Sciences Neurologiques, Hôpital de l'Enfant-Jésus, 1401, 18e Rue, Québec
H. Barbeau
Affiliation:
Centre de Recherche en Neurobiologie, École de Réadaptation, Université Laval, and Département des Sciences Neurologiques, Hôpital de l'Enfant-Jésus, 1401, 18e Rue, Québec
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Dynamic muscle function was evaluated in nine patients with Friedreich's ataxia (FA) and eight with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). The measurement of torque throughout maximum voluntary isokinetic knee movements was used to quantitatively describe muscle weakness in the ataxic patients. Both FA and ARSACS patients were shown to have decreased dynamic strength in comparison to normal values during knee extension and flexion movements at 30% /s. In the FA patients a lower torqueproducing capacity was seen in the older patients.

The electromyographic (EMG) activity was recorded in lower extremity muscles during the movements. In the vastus lateralis (VL), deviations from the normal EMG activation pattern were described in both groups of patients. A reduced amplitude in the EMG activity in the medial hamstrings (MH) was seen in the majority of the patients. An index of coactivation was defined by comparing the EMG activity when a muscle lengthened (antagonistic) to the EMG activity when the same muscle shortened (agonistic) during the isokinetic contractions. In comparison to normal values increased coactivation indexes were present in the VL and MH in patients of both groups. The characteristics of dynamic muscle strength and the activation of agonistic and antagonistic muscles described in the present study will provide the basis of evaluation for the effects of therapy in these patients.

Type
Quebec Cooperative Study of Friedreich's Ataxia
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 4 , November 1980 , pp. 367 - 377
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

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