Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-16T19:22:39.366Z Has data issue: false hasContentIssue false
  • English
  • Français

What Can Our Nose Tell Us About Possible Treatments for Alzheimer’s Disease?

Published online by Cambridge University Press:  02 December 2014

Samuel Weiss
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Information
Canadian Journal of Neurological Sciences , Volume 30 , Issue 1 , February 2003 , pp. 3
Copyright
Copyright © The Canadian Journal of Neurological 2003

References

1. Tropepe, V, Craig, CG, Morshead, CM, van der Kooy, D. Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma. J Neurosci 1997;17:7850–7859.Google Scholar
2. Roberts, E. Alzheimer’s disease may begin in the nose and may be caused by aluminosilicates. Neurobiol Aging 1986;7:561–567.Google Scholar
3. Magavi, SS, Leavitt, BR, Macklis, JD. Induction of neurogenesis in the neocortex of adult mice. Nature 2000;405:951–955.Google Scholar
4. Gould, E, Reeves, AJ, Graziano, MS, Gross, CG. Neurogenesis in the neocortex of adult primates. Science 1999;286:548–552.Google Scholar
5. Christen-Zaech, S, Kraftsik, R, Pillevuit, O. Early Olfactory Involvement in Alzheimer’s Disease. Can J Neurol Sci 2003; 30:20–25 Google Scholar
6. Arvidsson, A, Collin, T, Kirik, D, Kokaia, Z, Lindvall, O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002;8:963–970.Google Scholar
7. Murphy, C, Gilmore, MM, Seery, CS, Salmon, DP, Lasker, BR. Olfactory thresholds are associated with degree of dementia in Alzheimer’s disease. Neurobiol Aging 1990;11:465–469.CrossRefGoogle ScholarPubMed
8. Perl, DP, Good, PF. Uptake of aluminium into central nervous system along nasal-olfactory pathways. Lancet 1987;1:1028.Google Scholar
9. Miklossy, J, Kraftsik, R, Pillevuit, O, et al. Curly fiber and tangle-like inclusions in the ependyma and choroid plexus--a pathogenetic relationship with the cortical Alzheimer-type changes? J Neuropathol Exp Neurol 1998;57:1202–1212.Google Scholar
10. van der Kooy, D, Weiss, S. Why stem cells? Science 2000;287:1439–1441.Google Scholar
11. Kornack, DR, Rakic, P. The generation, migration, and differentiation of olfactory neurons in the adult primate brain. Proc Natl Acad Sci USA 2001;98:4752–4757.Google Scholar
12. Mesholam, RI, Moberg, PJ, Mahr, RN, Doty, RL. Olfaction in neurodegenerative disease: a meta-analysis of olfactory functioning in Alzheimer’s and Parkinson’s diseases. Arch Neurol 1998;55:84–90.Google Scholar