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Abnormal origins of the coronary arteries from the aortic root

Published online by Cambridge University Press:  23 April 2014

Julien I.E. Hoffman*
Affiliation:
Department of Pediatrics, University of California, San Francisco, CA, United States of America
*
Correspondence to: J. I. E. Hoffman, Professor of Pediatrics (Emeritus), Department of Pediatrics, University of California, San Francisco, 925 Tiburon Boulevard, Tiburon, CA 94920-1525, United States of America. Tel: 415 497 6741; Fax: 415 435 6941; E-mail: julien.hoffman@ucsf.edu

Abstract

Anomalous origin of a coronary artery from the aorta is a potentially serious anomaly that occurs in about 0.1–0.2% of the population. This percentage is small; however, it translates into about 4000 annual births with these anomalies. The clinical presentation of these anomalies is rare, and hence most are and will remain asymptomatic. The various anatomic anomalies are described, with anomalous origin of the left coronary artery that then passes between the aorta and pulmonary artery being the most serious of these anomalies. The pathophysiology resulting from these anomalies is described, as are methods for identifying those who require treatment; however, we still do not know the best methods of determining which patients need treatment.

Type
Review Articles
Copyright
© Cambridge University Press 2014 

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