Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-22T14:07:30.914Z Has data issue: false hasContentIssue false
  • English
  • Français

Anaphylactic shock after amiodarone infusion resulting in haemodynamic collapse requiring a temporary ventricular assist device

Published online by Cambridge University Press:  18 December 2013

Konstantin Averin ,
Angela Lorts  and
Chad Connor
Konstantin Averin*
Affiliation:
Cincinnati Children’s Hospital Medical Center, The Heart Institute, Cincinnati, Ohio, United States of America
Angela Lorts
Affiliation:
Cincinnati Children’s Hospital Medical Center, The Heart Institute, Cincinnati, Ohio, United States of America
Chad Connor
Affiliation:
Cincinnati Children’s Hospital Medical Center, The Heart Institute, Cincinnati, Ohio, United States of America
*
Correspondence to: Dr K. Averin MD, 3333 Burnet Ave, Cincinnati, OH 45229, United States of America. Tel: (513) 636-3863; Fax: (513) 636-3952; E-mail: konstantin.averin@cchmc.org
Get access Rights & Permissions [Opens in a new window]

Abstract

Acute heart failure related to anaphylactic shock is often reversible and necessitates aggressive support to ensure full recovery. We report the case of a 15-year-old boy who developed severe ventricular dysfunction and haemodynamic instability after administration of amiodarone and required temporary mechanical circulatory support with a left ventricular assist device. He had full recovery of cardiac function and returned to baseline neurologic status. This is the first report of successful left ventricular assist device use for recovery from cardiovascular collapse due to anaphylaxis.

Keywords

AmiodaroneanaphylaxisHeart Assist Deviceventricular dysfunctionheart failure
Type
Brief Reports
Information
Cardiology in the Young , Volume 25 , Issue 1 , January 2015 , pp. 164 - 166
Copyright
© Cambridge University Press 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Hartmann, M, Bode, C, Zirlik, A. Anaphylactic shock-associated cardiomyopathy. Int J Cardiology 2008; 127: E136–E137.CrossRefGoogle ScholarPubMed
2. Yalcin, F. Anaphylactic shock due to intravenous amiodarone. Am J Emerg Med 2012; 30: 265.e1–2.Google Scholar
3. Felix, SB, Baumman, G, Berdel, WE. Systemic anaphylaxis-separation of cardiac reactions from respiratory and peripheral vascular events. Res Exp Med 1990; 190: 239–252.Google Scholar
4. Almond, CS, Singh, TP, Gauvreau, K, et al. Extracorporeal membrane oxygenation for bridge to heart transplantation among children in the United States: analysis of data from the organ procurement and transplant network and extracorporeal life support organization registry. Circulation 2011; 123: 2975–2984.Google Scholar
5. Vultaggio, A, Matucci, A, Del Pace, S, et al. Tako-Tsubo-like syndrome during anaphylactic reaction. Eur J Heart Fail 2007; 9: 209–211.Google Scholar
6. Lyon, AR, Rees, PS, Prasad, S, et al. Stress (Takotsubo) cardiomyopathy – a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning. Nat Clin Pract Cardiovasc Med 2008; 5: 22–29.Google Scholar
7. Kounis, NG. Kounis syndrome (allergic angina and allergic myocardial infarction): a natural paradigm? Int J Cardiol 2006; 110: 7–14.CrossRefGoogle ScholarPubMed
8. Fransi, S, Breides, J. Anaphylaxis to intravenous amiodarone. Anaesth Intensive Care 2004; 32: 578–579.CrossRefGoogle ScholarPubMed
9. Thiagarajan, RR, Almond, CS, Cooper, DS, Morales, DLS. Ventricular assist devices for mechanical circulatory support in children. World J Pediatr Congenit Heart Surg 2012; 3: 104–109.CrossRefGoogle ScholarPubMed
10. Morel, OL, Jesel, N, Morel, A, et al. Transient left ventricular dysfunction syndrome during anaphylactic shock: vasospasm, Kounis syndrome or epinephrine-induced stunned myocardium? Int J Cardiol 2009; 145: 501–503.Google Scholar