Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-17T03:24:40.703Z Has data issue: false hasContentIssue false

Aortic vasculopathy with aneurysm: a rare cause of fetal hydrops

Published online by Cambridge University Press:  19 August 2008

Teo Nissen
Affiliation:
Department of Pathology, University of California, San Francisco, CA, USA
Norman H. Silverman
Affiliation:
Department of Pediatrics, University of California. San Francisco, CA, USA
Philip C. Ursell*
Affiliation:
Department of Pathology, University of California, San Francisco, CA, USA
*
Philip C Ursell, MD, Department of Pathology, University of California, San Francisco, CA 94143–0506 Tel (415) 476–6912, Fax (415) 476–9672, E-mail pursell@itsa.ucsf.edu

Abstract

An hydropic fetus seen at 28-weeks gestation had a saccular aortic aneurysm in the descending thoracic aorta. Histology disclosed marked fibrointimal hyperplasia, thrombus, and attenuation of the tunica media. The remainder of the descending thoracic aorta showed fibrointimal hyperplasia. We speculate that the narrowed lumen and rigid aortic wall resulting from this vasculopathy provided an increased afterload leading to cardiac failure.

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 2000

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Machin, GA. Hydrops revisited: Literature review of 1,414 cases published in the 1980s. Amer J Med Genet 1989; 34: 366390.CrossRefGoogle Scholar
2.Rudolph, AM. Aortic coarctation and isthmus narrowing. In: Congenital Diseases of the Heart. 1974, Year Book Medical Publishers Inc., Chicago: 329359.Google Scholar
3.Ball, RY. Ruptured abdominal aortic aneurysm in a stillborn fetus. Virchows Arch 1983; 399: 237244.CrossRefGoogle Scholar
4.Malee, MP, Cart, S, Rubin, LP, Johal, J, Feit, L. Prenatal ultrasound diagnosis of abdominal aortic aneurysm with fibrotic occlusion in aortic branch vessels. Prenat Diag 1997; 17: 479482.3.0.CO;2-A>CrossRefGoogle ScholarPubMed
5.Chen, S, Barner, HB, Fagan, LF, Kaiser, GC, Mudd, JFG, Willman, VL. Aortic aneurysm in childhood: Report of six instances.J Pediatr 1976; 89: 231234.CrossRefGoogle ScholarPubMed
6.Fricker, FJ, Park, SC, Neches, WH, Mathews, RA, Lerberg, DB. Aneurysm of the aorta in children. Chest 1979; 76: 305309.CrossRefGoogle ScholarPubMed
7.Siegal, MJ, McAlister, WH. Aortic aneurysms in children. Radiology 1979; 132: 615617.CrossRefGoogle Scholar
8.Sarkisov, DS, Kolocolchicova, EG, Varava, BN, Tjurmin, AV, Peclo, MM, Printseva, OY. Morphogenesis of intimal thickening in nonspecific aortoarteritis. Hum Pathol 1989; 20: 10481056.CrossRefGoogle ScholarPubMed
9.Bestetti, RB, Attab dos Santos, JL, Neto, EM, Oliveira, JS. Giant aneurysm of the ascending aorta secondary to medial agenesis in infancy. Chest 1993; 104: 296297.CrossRefGoogle ScholarPubMed
10.Rosen, S, Falk, RJ, Jennette, JC. Polyarteritis nodosa, including microscopic form and renal vasculitis. In: Systemic Vasculitides. Churg, A, Churg, J. editors, 1991, Igaku-Shoin, New York: 5799.Google Scholar