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Lung Abscess in Adults with Tetralogy of Fallot and Pulmonary Atresia

Published online by Cambridge University Press:  22 February 2010

Clare P. O’Donnell ,
Michael J. Landzberg  and
Mary P. Mullen
Clare P. O’Donnell
Affiliation:
Department of Cardiology, Children’s Hospital, 300 Longwood Avenue, Boston, MA, 02115
Michael J. Landzberg
Affiliation:
Department of Cardiology, Children’s Hospital, 300 Longwood Avenue, Boston, MA, 02115
Mary P. Mullen*
Affiliation:
Department of Cardiology, Children’s Hospital, 300 Longwood Avenue, Boston, MA, 02115
*
Correspondence to: Mary P. Mullen, MD, PhD, Department of Cardiology, Children’s Hospital, 300 Longwood Avenue, Boston, MA 02115. Tel: 617-355-7866; Fax: 617-713-3808; E-mail: mary.mullen@cardio.chboston.org
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Abstract

We describe 5 adults with tetralogy of Fallot and pulmonary atresia who developed lung abscesses, including some infected with atypical microbial pathogens, with important morbidity. We hypothesize that patients with such anatomy are at risk for chronic pulmonary infection due to hypo-perfusion of the pulmonary parenchyma. This previously unreported clinical association should be considered in the differential diagnosis of patients with tetralogy of Fallot and pulmonary atresia who alter their respiratory state.

Keywords

Adult congenital heart diseasepulmonary atresia and ventricular septal defectpulmonary disease
Type
Brief Reports
Information
Cardiology in the Young , Volume 20 , Issue 1 , February 2010 , pp. 91 - 93
Copyright
Copyright © Cambridge University Press 2010

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References

1.Kreutzer, J, Perry, SB, Jonas, RA, Mayer, JE, Castaneda, AR, Lock, JE. Tetralogy of Fallot with diminutive pulmonary arteries: preoperative pulmonary valve dilation and transcatheter rehabilitation of pulmonary arteries. J Am Coll Cardiol 1996; 27: 1741–1747.CrossRefGoogle ScholarPubMed
2.Bertoli, AM, Tabares, AH, Casas, JP, Saurit, V, Caeiro, F, Alarellos, A. Lung cavitation in primary antiphospholipid syndrome. Lupus 2002; 11: 57–59.Google Scholar
3.Morgenthaler, TI, Ryu, JH, Utz, JP. Cavitary pulmonary infarct in immunocompromised hosts. Mayo Clin Proc 1995; 70: 66–68.Google Scholar
4.Libby, LS, King, TE, LaForce, FM, Schwarz, MI. Pulmonary cavitation following pulmonary infarction. Medicine (Baltimore) 1985; 64: 342–348.Google Scholar
5.Leggiadro, RJ, Dover, GJ, Morse, ML, Santosham, M. Lung abscess in sickle cell disease. Am J Pediatr Hematol Oncol 1982; 4: 215–217.Google ScholarPubMed
6.Hirshberg, B, Sklair-Levi, M, Nir-Paz, R, Ben Sira, L, Krivoruk, V, Kramer, MR. Factors predicting mortality of patients with lung abscess. Chest 1999; 115: 746–750.Google Scholar
7.Mwandumba, HC, Beeching, NJ. Pyogenic lung infections: factors for predicting clinical outcome of lung abscess and thoracic empyema. Curr Opin Pulm Med 2000; 6: 234–239.CrossRefGoogle ScholarPubMed
8.Mori, T, Ebe, T, Takahashi, M, Isonuma, H, Ikemoto, H, Oguri, T. Lung abscess: analysis of 66 cases from 1979 to 1991. Intern Med 1993; 32: 278–284.Google Scholar
9.Reed, WP. Indolent pulmonary abscess associated with Klebsiella and Enterobacter. Am Rev Respir Dis 1973; 107: 1055–1059.Google Scholar
10.Jawad, AF, McDonald-Mcginn, DM, Zackai, E, Sullivan, KE. Immunologic features of chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome). J Pediatr 2001; 139: 715–723.Google Scholar